水针迎香穴联合“促嗅汤”治疗感觉神经性嗅觉障碍的疗效研究  

Clinical study of 120 cases with nervous anosmia treated by combining hydroacupuncture of Yingxiang Xue with Cu Xiu decoction

作　　者：李艳青 顾思远 臧朝平 张重华 LI Yanqing;GU Siyuan;ZANG Chaoping;ZHANG Chonghua(Department of Otolaryngology, Eye Ear Nose and Throat Hospital of Fudan University, Shanghai 200031, China)

机构地区：[1]复旦大学附属眼耳鼻喉科医院耳鼻喉科名中医工作室,上海200031

出　　处：《中国中西医结合耳鼻咽喉科杂志》2019年第1期29-34,共6页Chinese Journal of Otorhinolaryngology in Integrative Medicine

基　　金：上海市进一步加快中医药事业发展三年行动计划(2014-2016年)资助(编号:ZY3-JSFC-1-1021);"张重华全国名老中医专家传承工作室"建设项目的资助;第六批全国老中医药专家学术经验继承工作项目的资助

摘　　要：目的观察不同组别感觉神经性嗅觉障碍患者的临床疗效,探索更加有效的嗅觉障碍治疗方法。方法将120例感觉神经性嗅觉障碍患者,随机分为西药组、水针组、中药组和综合组,每组30例。西药组采用短期小剂量口服泼尼松片,联合鼻用激素治疗;水针组在常规西药治疗基础上采用双侧迎香穴穴位注射;中药组在西药治疗同时,口服自制验方"促嗅汤";综合组联合应用西药、水针和中药。每组患者2周随访一次,疗程均为3个月。采用日本T&T嗅试剂检测嗅觉功能,进行疗效评定。结果 (1)西药组有效率最低(20%),水针组(56.7%)、中药组(46.7%)和综合组疗效均显著优于西药组(P<0.05);(2)综合组有效率最高(63.3%),但水针组和中药组、水针组和综合组、中药组和综合组之间的疗效均无显著差异(P>0.05);(3)疗效与患者性别、年龄、病因、病程、嗅功能分度无显著相关(P>0.05),与患者分组即治疗方式显著相关(P<0.05)。结论中药联合水针迎香穴用于治疗感觉神经性嗅觉障碍,具有内外兼治的优势,疗效肯定,且无明显不良反应,是一种较有前途的嗅觉障碍治疗方法,值得进一步深入研究。Objective To observe the clinical efficacy of different groups of neurological olfactory disorder, and explore more effective treatments. Methods The researchers randomized 120 patients with sensorineural olfactory disorders into western medicine group, hydro-acupuncture group, traditional Chinese medicine group and integrated group, with 30 cases in each group. Western medicine group combined the short-term low-dose oral prednisone with nasal hormone therapy. Bilateral Yingxiang acupoint injection was used in hydro-acupuncture group based on the conventional western medicine treatment. Chinese medicine group took Cu Xiu Decoction with western medical treatment at the same time. Integrated group took western medicine, hydro-acupuncture and traditional Chinese medicine. Patients were followed up every 2 weeks for a period of 3 months. Japanese T & T sniffing reagent was used to detect olfactory function and conduct the efficacy evaluation. Results ①Western medicine group had the lowest effective rate (20%), while effective rates of hydro-acupuncture group (56.7%), medicine group (46.7%) and integrated group were significantly higher than that of western medicine group (P<0.05);② Integrated group had the highest effect rate (63.3%), but there were no significantly differences between hydro-acupuncture group and medicine group, hydro-acupuncture group and integrated group, and medicine group and integrated group (all P>0.05);③ There was no significant correlation between curative effect and sex, age, etiology, course of disease, score of olfactory function (P>0.05), but there was significant correlation between curative effect and treatment method (P<0.05). Conclusion Combining water injection Yingxiang acupoint with traditional Chinese medicine was a promising method for sensorineural olfactory dysfunction, which had the advantages of internal and external treatment, definite clinical curative effect and no obvious adverse reactions. It was worthy of further study.

关 键 词：感觉神经性嗅觉障碍 穴位注射 “促嗅汤” 临床疗效 

分 类 号：R276.1[医药卫生—中医五官科学]