老年男性2型糖尿病患者骨密度及骨质疏松率的比较分析  

Comparative Analysis of Bone Mineral Density and Osteoporosis Prevalence in Elderly Male Patients with Type 2 Diabetes Mellitus

作　　者：曹宗锐[1] 屈晓龙 屈波 郑博 陈天逸 张秀莉 蒋涛[1] Cao Zongrui;Qu Xiaolong;Qu Bo;Zheng Bo;Chen Tianyi;Zhang Xiuli;Jiang Tao(Department of Orthopaedics,The First Affiliated Hospital of Chengdu Medical College,Chengdu 610500,China)

机构地区：[1]成都医学院第一附属医院骨科,成都610500

出　　处：《成都医学院学报》2019年第1期52-55,共4页Journal of Chengdu Medical College

基　　金：四川省科技厅科技支撑项目(No:2015SZ0167)

摘　　要：目的评估老年男性2型糖尿病患者骨密度及骨质疏松情况,为临床老年男性2型糖尿病患者骨质疏松管理提供指导。方法收集2016年8月至2018年10月成都医学院第一附属医院60～80岁老年男性2型糖尿病患者163例作为观察组,209例60～80岁正常老年男性作为对照组,使用双能X线骨密度测量仪测量其骨密度,比较两组骨密度及骨质疏松流行率。结果老年男性2型糖尿病患者股骨颈、腰1～腰4、股骨大粗隆骨密度<对照组,差异有统计学意义(P<0.05)。老年男性2型糖尿病患者股骨颈、腰1～腰4、股骨大粗隆骨质疏松患病率>对照组,差异有统计学意义((P<0.05),股骨大粗隆骨质疏松患病率两组差异无统计学意义(P>0.05)。结论 60～80岁老年男性2型糖尿病患者骨密度小于对照组,骨质疏松流行率大于对照组,应进行骨质疏松管理,以阻止发生严重骨质疏松性脆性骨折,造成严重经济负担。Objective To assess the bone mineral density and osteoporosis prevalence in elderly male patients with type 2 diabetes mellitus(T2DM)and provide guidance for the clinical management of osteoporosis in elderly male patients with T2DM.Methods A total of 163 male T2DM patients aged between 60 and 80 and treated in The First Affiliated Hospital of Chengdu Medical College from August of 2016 to October of 2018 were selected into the observation group,and the other 209 healthy men aged between 60 and 80 were enrolled into the control group.The bone mineral density was measured by dual-energy X-ray absorptiometry,and the bone mineral density and osteoporosis prevalence were compared between the two groups.Results The bone mineral density of the femoral neck,lumbar between fist segment and fourth segment,and femur trochanter was significantly lower in the observation group than in the control group(P<0.05),while the osteoporosis prevalence in the femoral neck and lumbar between fist segment and fourth segment was significantly higher in the observation group than in the control group(P<0.05).There was no significant difference in the osteoporosis prevalence of femur trochanter between the two groups(P>0.05).Conclusion The bone mineral density of the male T2DM patients aged between 60 and 80 is lower and their osteoporosis prevalence is higher when compared with the healthy men with the same age,therefore,the management of osteoporosis should be implemented to prevent the occurrence of severe osteoporotic fragility fractures causing serious economic burden.

关 键 词：老年男性 2型糖尿病 骨密度 骨质疏松 

分 类 号：R58[医药卫生—内分泌]