早期外伤性脑梗死的MRS及MRI临床分析  

Clinical analysis of MRS and MRI in early traumatic cerebral infarction

作　　者：陈云鹏 李在雨[2] 杨正月 颜杰浩[3] CHEN Yunpeng;LI Zaiyu;YANG Zhengyue;YAN Jiehao(Nanshan People′ s Hospital ofShenzhen,Shenzhen,518052,China;Department of Neurosurgery;Department of Neurosurgery)

机构地区：[1]广西中医药大学附属第一医院神经外科,广西南宁530023 [2]深圳大学附属罗湖医院神经外科,广东深圳518000 [3]深圳市南山区人民医院神经外科,广东深圳518052

出　　处：《岭南现代临床外科》2019年第1期80-82,共3页Lingnan Modern Clinics in Surgery

基　　金：惠州市科技计划项目(20140805)

摘　　要：目的探讨MRI及MRS对外伤性脑梗死的早期诊断、及时治疗和判断预后的临床指导价值。方法对51例外伤性脑梗死患者分为三组行影像学(MRI及MRS)检查,并检测其外伤性脑梗死区内一些代谢物(如NAA,Cho, Lac等)的含量变化,然后对其代谢物进行量化分析。结果三组病例头部MRI平扫/增强、DWI检查梗死区及其周围范围有不同程度的异常信号变化,提示梗死区存在不同程度的水肿和缺血现象。MRS检查示外伤性脑梗死中心区,NAA下降明显,Cho上升明显,Lac上升明显,出现Lac峰,而脑梗死中心周边的缺血半暗带区,NAA轻度降低,Cho轻度上升,Lac上升不明显/不上升。结论 MRI及MRS检查可对伤性脑梗死的临床早期诊断提供有效价值,并可初步判断其治疗预后。Objective To investigate the clinical guiding value of MRI and MRS in the early diagnosis,timely treatment and prognosis of traumatic cerebral infarction. Methods Imaging(MRI and MRS) examination fifty-one patients with traumatic cerebral infarction were divided into three groups for,and detected the content changes of some metabolites(such as NAA,Cho,Lac,etc.)in the area of traumatic cerebral infarction,and then analyzed the metabolites quantitatively. Results There were different degrees of abnormal signal changes in the infarct area and its surrounding area on MRI head plain scan and enhancement scan and DWI in the three groups of patients,suggesting that there were different degrees of edema and ischemia in the infarct area. MRS showed that in the central area of traumatic cerebral infarction,NAA decreased significantly,Cho increased significantly,Lac increased significantly, and Lac peak appeared. In the ischemic penumbra area around the center of cerebral infarction,NAA decreased slightly,Cho increased slightly,and Lac no significant increased. Conclusion MRI and MRS can provide effective value for the early clinical diagnosis of traumatic cerebral infarction and preliminarily determine the therapeutic prognosis.

关 键 词：MRS MRI 颅脑外伤 外伤性脑梗死 

分 类 号：R445[医药卫生—影像医学与核医学]