包头市部分地区新生儿脐带血麻疹和风疹抗体相关调查  

Correlative investigation of neonatal umbilical cord blood antibody against measles and rubella in some areas of Baotou city

作　　者：那诗卉 闫绍宏 NA Shihui;YAN Shaohong(Baotou Medical College,Inner Mongolia,Baotou 014060,China)

机构地区：[1]内蒙古科技大学包头医学院,内蒙古包头014060

出　　处：《包头医学院学报》2019年第1期73-75,共3页Journal of Baotou Medical College

摘　　要：目的:了解包头市新生儿脐带血麻疹、风疹胎传抗体水平,为降低小月龄婴儿麻疹、风疹发病率提供依据。方法:在包头市的五家医院收集产妇脐带血血清样本,通过酶联免疫吸附试验(ELISA)对麻疹以及风疹的胎传抗体进行检测研究。结果:111例新生儿脐带血麻疹IgG抗体阳性率为94.59%,风疹IgG抗体阳性率为81.98%,麻疹几何平均浓度(GMC)为546.70 mIU/mL,风疹几何平均浓度(GMC)为30.95 mIU/mL。脐带血的母传麻疹、风疹抗体水平与母亲的年龄及新生儿的胎龄差异均有统计学意义。结论:新生儿脐带血胎传抗体水平与母亲抗体水平呈正相关关系,母亲年龄与胎龄是影响脐带血麻疹和风疹胎传抗体的因素。Objective:To explore the level of measles and rubella antibody in neonatal umbilical cord blood in Baotou,and to provide scientific basis for controlling the incidence of measles and rubella in infants.Methods:The blood serum of maternal umbilical cord was collected from five hospitals in Baotou using the ELISA to detect measles and rubella antibody levels.Results:Among 111 neonates,the positive rate of measles and rubella was 94.59% and 81.98%;the geometric mean concentration(GMC)of measles and rubella was 546.70mIU/ml and 30.95mIU/ml.There were statistically significant differences between maternal measles and rubella antibody levels in umbilical cord blood and maternal age and fetal age in neonates.Conclusion:There is a positive correlation between fetal antibody level and maternal antibody level in neonatal umbilical cord blood.Maternal age and gestational age are the factors affecting fetal transmission of antibodies against measles and rubella in umbilical cord blood.

关 键 词：麻疹 风疹 脐带血 胎传抗体 育龄期妇女 新生儿 

分 类 号：R725.1[医药卫生—儿科] R186[医药卫生—临床医学]