中药组方贴敷联合非甾体抗炎药治疗亚急性甲状腺炎临床对照研究  

Clinical control study of traditional Chinese medicine external application combined with non-steroidal anti-inflammatory drugs in the treatment of subacute thyroiditis

作　　者：乔静[1] 李蕾 张建国[1] 孙述栋[1] QIAO Jing;LI Lei;ZHANG Jianguo;SUN Shudong(Department of Endocrinology,Gaomi People's Hospital in Shandong Province,Gaomi 261500,China)

机构地区：[1]山东省高密市人民医院内分泌科,山东高密261500

出　　处：《中国现代医生》2019年第4期74-77,共4页China Modern Doctor

摘　　要：目的对照研究中药外用贴敷联合非甾体抗炎药治疗亚急性甲状腺炎临床疗效。方法选取2015年2月～2017年7月我院就诊的162例亚急性甲状腺炎患者,将其随机分为治疗组和对照组,其中治疗组90例采用中西医结合疗法,对照组72例采用西药治疗,观察比较两组患者症状改变,检测血沉、游离三碘甲状腺原氨酸、游离甲状腺素、促甲状腺激素水平。结果治疗组和对照组总有效率为92.2%、87.5%,痊愈率分别达到74.4%、47.2%,比较差异有统计学意义(P<0.05)。两组甲减发生率、亚甲炎复发率分别为7.8%、15.3%、3.0%、8.8%,比较差异有统计学意义(P<0.05)。结论治疗组方案发扬中药全面调理和西药快速解除症状的双重作用。中药干预可促进甲状腺功能恢复,减轻亚甲炎炎性反应,尤其在降低复发率及甲减发生率方面有积极意义。Objective To study the clinical efficacy of external application of traditional Chinese medicine combined with non-steroidal anti-inflammatory drugs in the treatment of subacute thyroiditis. Methods 162 patients with subacute thyroiditis who were admitted to our hospital from February 2015 to July 2017 were randomly divided into treatment group and control group. 90 patients in the treatment group were treated with integrated Chinese and Western medicine, and 72 patients in the control group were treated with western medicine. Symptom changes were observed in both groups, and erythrocyte sedimentation rate, free triiodothyronine, free thyroxine, and thyroid stimulating hormone levels were measured and compared between the two groups. Results The total effective rate of the treatment group and the control group was 92.2% and 87.5%, and the cure rate was 74.4% and 47.2%, respectively. The differences were statistically significant(P<0.05). The incidence of hypothyroidism and recurrence rate of methylene inflammation were 7.8%, 15.3%, 3.0% and 8.8%, respectively, and the differences were statistically significant(P<0.05). Conclusion The combination of Chinese and western medicine has the dual advantages of comprehensive conditioning of traditional Chinese medicine and rapid relief of symptoms of western medicine. Chinese medicine intervention can promote the recovery of thyroid function and reduce the inflammatory response of subacute thyroiditis, especially to reduce the recurrence rate and the incidence of hypothyroidism.

关 键 词：亚急性甲状腺炎 中药贴敷 中西医结合 非甾体抗炎药 

分 类 号：R259[医药卫生—中西医结合]