人参灵芝胶囊缓解体力疲劳小鼠的试验  

Study on the Effects of the Ginseng Ganoderma Capsules on Physical Fatigue Alleviation in Mice

作　　者：苏婧婧 李庆林 SU Jing-jing;LI Qing-lin(Key Laboratory of Xin’an Medicine, Ministry of Education, Anhui Province Key Laboratory of R&D of Traditional Chinese Medicine, Anhui University of Chinese Medicine, Hefei,Anhui 230038)

机构地区：[1]安徽中医药大学科研实验中心新安医学教育部重点实验室,安徽合肥230038

出　　处：《安徽农业科学》2019年第5期176-177,198,共3页Journal of Anhui Agricultural Sciences

摘　　要：[目的]考察人参灵芝胶囊缓解实验性小鼠体力疲劳的作用。[方法]小鼠连续灌胃给予不同剂量(0.9、0.6、0.3 g/kg)的人参灵芝胶囊,阴性对照组给予等量蒸馏水。连续灌胃30 d后,测定小鼠负重游泳时间、运动后血清尿素含量、血乳酸含量、肝糖原含量。[结果]与阴性对照组比较,高、中剂量组小鼠负重游泳时间显著延长,各给药组血清尿素含量明显降低,各给药组肝糖原含量明显升高,中剂量组小鼠游泳后20 min血乳酸值和血乳酸曲线下面积显著降低。[结论]人参灵芝胶囊具有缓解体力疲劳的作用。[Objective] The research aimed to investigate the alleviate physical fatigue effects of ginseng ganoderma capsules in mice.[Method] Kunming male mice were randomly divided into 4 groups according to different doze, the low, the medium and the high dosage groups of ginseng ganoderma capsules(0.3,0.6,0.9 g/kg) and the blank control group.Each mouse was orally administered once a day for 30 days.After the end of the administration, all the mice were evaluated for their weight loaded swimming duration, the contents of blood urea nitrogen, blood lactic acid and the hepatic glycongen.[Result] Compared with the blank control group, the high and medium dose of ginseng ganoderma capsules groups could prolong the loaded swimming time, the three dose could decrease the contents of blood urea and increase the content of hepatic glycogen. In addition, the medium dose of ginseng ganoderma capsules group could reduce the blood lactate value and the area under the curve of blood lactate after 20 min swimming in mice.[Conclusion] Ginseng Ganoderma capsules possess relieving physical fatigue effect.

关 键 词：人参灵芝胶囊 缓解体力疲劳 负重游泳时间 血清尿素 血乳酸 肝糖原 

分 类 号：R285.5[医药卫生—中药学]