延迟结扎脐带对产妇免疫球蛋白水平及产后出血影响的作用研究  

Effect of Delayed Ligation of Umbilical Cord on the Levels of IgG and IgM in Puerpera and Postpartum Hemorrhage

作　　者：郑凤英[1] 孟彤 周丽 ZHENG Feng-ying;MENG Tong;ZHOU Li(Department of Obstetrics,Xinhua Hospital,Beijing Friendship Hospital,Capital Medical University,Beijing 101100,China;Department of Obstetrics,Tongzhou District Maternal and Child Health Hospital,Beijing 101100,China)

机构地区：[1]首都医科大学附属北京友谊医院新华医院产科,北京101100 [2]北京市通州区妇幼保健院产科,北京101100

出　　处：《标记免疫分析与临床》2019年第2期201-204,共4页Labeled Immunoassays and Clinical Medicine

基　　金：北京市通州区科技计划项目(编号:KJ2017CX069)

摘　　要：目的分析延迟结扎脐带对产妇免疫球蛋白(IgA、IgG和IgM)水平及产后出血等的影响作用。方法选取本院2017年1月至2017年12月间在本院分娩的健康产妇200例纳入本研究。随机分为两组,观察组包含100例受试对象,采用延迟结扎脐带的期待处理方式;对照组100例受试对象,使用常规的分娩后立即结扎脐带的处理方式。分析延迟结扎脐带对产妇免疫球蛋白(IgA、IgG和IgM)水平及产后出血和再次妊娠的影响作用。采用SPSS17.0统计软件分析处理数据。结果观察组平均产后出血量167. 25±10.25mL,对照组产后出血量173. 03±10. 99mL,差异未见统计学意义,P>0.05。观察组产后出血总发生率低于对照组,差异有统计学意义,P<0.05;不同年龄组、不同分娩方式以及不同分娩次数的受试对象比较也均可见观察组的产后出血发生率更低,与对照组比较差异均有统计学意义,P<0. 05;两组不同特征的受试对象比较结果表明,观察组和对照组中均可见年龄<25岁的受试对象产后出血发生率低于年龄≥25岁的受试对象,差异有统计学意义,P<0.05;产后24 h比较两组受试对象的免疫水平,可见观察组与对照组产妇IgA、IgG和IgM的血清水平差异均未见统计学意义,均有P>0. 05;不同年龄组、不同分娩方式以及不同分娩次数的受试对象之间差异也未见统计学意义。且对于子宫复原具有积极意义。结论延迟结扎脐带对于各种年龄段、不同分娩方式以及不同分娩次数的产妇来说,均有减低产后出血发生风险的潜在作用;同时年龄越小,风险也会越低。脐带结扎时间对产妇产后的免疫状态以及近期预后的影响不大。Objective To analyze the effects of delayed ligation of umbilical cord on the levels of IgG and IgM in puerpera,postpartum hemorrhage. Methods 200 healthy puerperas delivered in our hospital from January 2017 to December 2017 were included in the study. Two groups were randomLy divided into two groups:the observation group consisted of 100 subjects,and the control group 100 subjects were treated with the routine treatment of umbilical cord ligation immediately after delivery. Analysis of the effect of delayed ligation of umbilical cord on the levels of IgG and IgM in puerpera The effect of postpartum hemorrhage and re-pregnancy. SPSS17.0 software package was used to analyze and process the data. Results The average postpartum hemorrhage volume in the observation group was 167.25±10.25mL,while that in the control group was 173.03 ±10.99mL. There was no significant difference between the two groups ( P >0.05). The total incidence of postpartum hemorrhage in the observation group was lower than that in the control group ( P <0.05). Compared with the control group,the difference was significant. The results showed that the incidence of postpartum hemorrhage was lower in the observation group and the control group than that in the age ≥ 25 group,and the incidence of postpartum hemorrhage was lower in the observation group and the control group than that in the age ≥ 25 group,and the incidence of postpartum hemorrhage was significantly lower in the two groups than in the age ≥ 25 group. The difference was statistically significant ( P <0.05),the immune level of the two groups was compared at 24 hours postpartum,there was no significant difference in the serum levels of IgA IgG and IgM between the observation group and the control group ( P >0.05). There was no statistical difference between subjects with different delivery patterns and times of delivery. And for the child The restoration of the palace is of positive significance. Conclusion Delayed ligation of umbilical cord can reduce the risk of postpartum he

关 键 词：延迟结扎 脐带 产妇 免疫球蛋白 产后出血 预后 

分 类 号：R714.461[医药卫生—妇产科学] R446.6[医药卫生—临床医学]