4D打印形状记忆聚合物在生物医疗领域的研究进展  

Development of 4D printed shape memory polymers in biomedical field

作　　者：李春妍 张风华 王亚立 郑威[1] 刘彦菊 冷劲松[2] LI ChunYan;ZHANG FengHua;WANG YaLi;ZHENG Wei;LIU YanJu;LENG JinSong(Research Center on Life Sciences and Environmental Sciences, Harbin University of Commerce, Harbin 150076, China;Center for Composite Materials and Structures, Harbin Institute of Technology, Harbin 150080, China;Department of Astronautical Science and Mechanics, Harbin Institute of Technology, Harbin 150001, China)

机构地区：[1]哈尔滨商业大学生命科学与环境科学研究中心,哈尔滨150076 [2]哈尔滨工业大学复合材料与结构研究所,哈尔滨150080 [3]哈尔滨工业大学航天工程与力学系,哈尔滨150001

出　　处：《中国科学：技术科学》2019年第1期13-25,共13页Scientia Sinica(Technologica)

基　　金：国家自然科学基金(批准号:11632005;11672086);国家自然科学基金创新研究群体项目(批准号:11421091)资助

摘　　要：形状记忆聚合物是一种在外界刺激条件下产生形状变化的智能材料, 4D打印是基于可变形材料和3D打印技术的一种综合性技术,可变形材料中形状记忆聚合物的应用最为广泛,目前4D打印形状记忆聚合物在各个领域都有应用,尤其是在生物医疗领域具有巨大的应用价值. 4D打印技术突破了传统医学领域个性化订制的技术瓶颈,为生物医疗领域的进一步发展提供了新的契机.本文首先综述了形状记忆聚合物、3D打印技术以及4D打印形状记忆聚合物在生物医疗领域的国内外研究进展,并介绍了4D打印形状记忆聚合物在生物医疗领域的实例和应用价值,最后总结了4D打印形状记忆聚合物在生物医疗领域的应用前景、存在的问题以及未来的发展方向.Shape memory polymers(SMPs)as a class of smart materials,can remember various shapes and return to their original shapes upon external stimuli.4D printing that is the combination of 3D printing and SMPs has been used for fabrication of various SMPs in many areas of science and technology.At present,4D printing technology plays an important role and shows promising applications in biomedical field.4D printing breaks through the technical bottleneck of customization in traditional medical field and provides a new opportunity for the further development of biomedical field.In this article,we review the research progress of SMPs,3D printing technology and 4D printed SMPs used in biomedical science.Moreover,we introduce some typical biomedical applications of 4D printing of SMPs.Furthermore,we summary the application prospects,existing problems and future development direction of 4D printed SMPs in biomedical field.

关 键 词：4D打印 形状记忆聚合物 复合材料 生物医疗 智能结构 

分 类 号：R318[医药卫生—生物医学工程]