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作 者:谢燕[1] XIE Yan(Dongtai City TCM Hospital,Dongtai,Jiangsu Province,China 224200)
出 处:《系统医学》2019年第2期23-25,共3页Systems Medicine
摘 要:目的探讨全麻、硬膜外麻醉对老年良性前列腺增生患者经尿道前列腺电切术治疗后认知功能的影响情况。方法选取该院于2015年2月—2018年7月期间收治的94例老年良性前列腺增生患者作为该次研究对象,利用随机数字表法将入选老年良性前列腺增生患者均分为研究组(n=47)、对照组(n=47)。两组老年良性前列腺增生患者均接受经尿道前列腺电切术治疗,对照组老年良性前列腺增生患者予以静脉吸入复合全身麻醉,研究组老年良性前列腺增生患者予以硬膜外麻醉。记录两组老年前列腺电切术患者手术前、术后MMSE量表评分变化情况及POCD发生率,将所得数据输入统计学软件后行相应分析。结果两组老年良性前列腺增生患者麻醉前MMSE量表评分分别为(23.20±1.09)分、(23.18±1.10)分,数据对比(t=0.088 5,P>0.05);术后2 h研究组老年良性前列腺增生患者MMSE量表评分分别为(21.94±1.67)分、(18.54±1.67)分(组间对比(t=9.869 5,组内对比t=4.331 5、15.907 3,P<0.05);研究组老年前列腺电切术患者术后POCD发生率(4.26%)显著低于对照组(19.15%),(χ~2=5.04,P<0.05)。结论应用硬膜外麻醉可显著减少老年前列腺电切术患者术后认知功能影响程度及POCD发生率,有利于保障麻醉安全性及患者生活质量。Objective To investigate the effect of general anesthesia and epidural anesthesia on cognitive function in patients with benign prostatic hyperplasia after transurethral resection of prostate.Methods A total of 94 elderly patients with benign prostatic hyperplasia admitted to our hospital from February 2015 to July 2018 were enrolled.The patients enrolled in the elderly with benign prostatic hyperplasia were randomly divided into study groups(n=47),control group(n=47).Two groups of elderly patients with benign prostatic hyperplasia were treated with transurethral resection of the prostate.In the control group,patients with benign prostatic hyperplasia were treated with intravenous inhalation combined with general anesthesia.The study group received epidural anesthesia in patients with benign prostatic hyperplasia.The changes of MMSE scale scores and POCD incidence before and after surgery were recorded in two groups of elderly patients undergoing prostatectomy.The data were input into statistical software and analyzed accordingly.Results The pre-anesthesia MMSE scale scores of the two groups of elderly patients with benign prostatic hyperplasia were(23.20±1.09)points,(23.18±1.10)points,and the data were compared with(t=0.088 5,P>0.05).The postoperative 2 h postoperative group of benign prostatic hyperplasia scores of patients with MMSE were(21.94±1.67),(18.54±1.67),and the comparison between groups(t=9.869 5,The intra-group contrast t=4.331 5,15.907 3,P<0.05).The elderly in the study group were treated with prostate resection.The incidence of postoperative POCD(4.26%)was significantly lower in the patients than in the control group(19.15%)(χ^2=5.04,P<0.05).Conclusion Epidural anesthesia can significantly reduce the influence of postoperative cognitive function and the incidence of POCD in elderly patients undergoing prostatectomy,which is beneficial to the safety of anesthesia and the quality of life of patients.
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