甲基三氧化铼催化过氧化氢氧化异丁香酚合成香兰素的研究  

Synthesis of vanillin by catalytic hydrogen peroxide oxidation of iso-eugenol catalyzed by methyl-trioxide

作　　者：何金义 朱凯[1] HE Jin-yi;ZHU Kai(Chemical Engineering Academy,Nanjing Forestry University,Nanjing 210037,China)

机构地区：[1]南京林业大学化学工程学院,江苏南京210037

出　　处：《应用化工》2019年第3期550-553,共4页Applied Chemical Industry

基　　金："十三五"国家重点研发计划(2018YFD0600405)

摘　　要：以异丁香酚为原料,叔丁醇为溶剂,CH_3ReO_3为催化剂,H_2O_2为氧化剂,进行氧化合成香兰素。采用单因素结合正交实验对异丁香酚氧化合成香兰素工艺进行优化。结果表明,最佳工艺条件为:反应温度70℃,反应时间4 h,催化剂用量0.9%(以异丁香酚的质量分数计)。在此条件下,反应稳定性较好,产物平均得率可达90.3%,产品香气较为纯正。采用IR、GC-MS、和~1H NMR等对产物进行了分析。Using isoeugenol as the raw material,t-butanol as solvent,CH3ReO3 as catalyst,H2O2 as oxidation to synthesize vanillin.The synthesis of vanillin by isoeugenol oxidation was optimized by single factor and orthogonal experiment.The result showed that the optimal conditions:reaction temperature 70 ℃, reaction time 4 h,the catalyst 0.9% and the yield was 90.3% of vanillin.The structure of the product was identified by FTIR,GC-MS and 1H NMR spectrum.

关 键 词：异丁香酚 CH3ReO3 H2O2 氧化 

分 类 号：TQ654[化学工程—精细化工]