以血液学改变为主要表现的HIV/AIDS患者52例临床分析  

Clinical Analysis of 52 Cases of HIV/AIDS Patients with Hematological Changes as the Main Manifestation

作　　者：黄中元[1] 苏海萍[1] 黄慧娟 HUANG Zhong-yuan;SU Hai-ping;HUANG Hui-juan(Department of Infectious Diseases,Hechi People's Hospital,Hechi,Guangxi,547000 China)

机构地区：[1]河池市人民医院传染科,广西河池547000

出　　处：《中外医疗》2019年第5期83-85,共3页China & Foreign Medical Treatment

摘　　要：目的探讨HIV/AIDS患者的血液学改变特点与临床表现。方法便利选择2016年9月—2017年9月期间该院收治的HIV/AIDS患者52例为研究对象,对其临床治疗资料进行回顾性分析。结果该组的52例患者中,22例皮肤瘀点瘀斑、30例发热、1例抽搐、3例皮疹、5例头痛、4例真菌感染、4例淋巴结肿大、5例乏力、6例慢性腹泻、11例气促、心悸以及头晕;血液学改变:①血常规。52例患者中,26例血色素低于正常范围,占50.00%,其中6例为轻度贫血,占11.54%,13例为中度贫血,占25.00%,7例重度贫血,占13.46%;18例血小板减少,占34.62%,34例白细胞减少,占65.38%,其中30例合并淋巴细胞百分比减少;②骨髓细胞数目及形态。52例患者中,13例骨髓细胞活力低下,占25.00%,其余39例活跃,占72.00%;26例粒系增生活跃,占50.00%,7例欠活跃,占13.46%,6例明显活跃,占11.54%;同时,患者治疗前后的外周血T淋巴细胞和VL变化比较差异有统计学意义(P<0.05)。结论艾滋病患者往往合并免疫功能低下,其骨髓和血液学改变存在着一定的特点。Objective To investigate the characteristics and clinical manifestations of hematological changes in HIV/AIDS patients.Methods A total of 52 HIV/AIDS patients admitted to our hospital from September 2016 to September 2017 were random selected as subjects,and their clinical treatment data were retrospectively analyzed.Results Of the 52 patients in this group,22 had ecchymosis,30 had fever,1 had convulsions,3 had rash,5 had headache,4 had fungal infection,4 had lymphadenopathy,and 5 had fatigue,6 had chronic diarrhea,11 cases of shortness of breath,palpitations and dizziness;hematological changes:1.blood routine.Of the 52 patients,26 had hypoglycemia below the normal range,accounting for 50.00%,of which 6 were mild anemia,accounting for 11.54%,13 were moderate anemia,accounting for 25.00%,and 7 were severe anemia,accounting for 13.46%;18 cases of thrombocytopenia,accounting for 34.62%,34 cases of leukopenia,accounting for 65.38%,of which 30 cases of combined lymphocyte percentage decreased;2.bone marrow cell number and morphology.Of the 52 patients,13 had lower bone marrow cell viability,accounting for 25.00%,and the remaining 39 were active,accounting for 72.00%;26 cases were active in granulocyte hyperplasia,accounting for 50.00%,7 cases were underactive,accounting for 13.46%,and 6 cases were significantly active of 11.54%;at the same time,the difference of peripheral blood T lymphocytes and VL before and after treatment was statistically significant(P<0.05).Conclusion AIDS patients often have low immune function,and their bone marrow and hematological changes have certain characteristics.

关 键 词：细胞免疫缺陷 血液学改变 艾滋病 

分 类 号：R5[医药卫生—内科学]