阿奇霉素与头孢派酮钠舒巴坦钠治疗老年肺炎  

Azithromycin and Cefoperazone Sodium and Sulbactam Sodium in the Treatment of Senile Pneumonia

作　　者：涂军[1] TU Jun(The First Department of Geriatrics,The Second People's Hospitalof Jingzhou City,Jingzhou Hubei 434000,China)

机构地区：[1]湖北省荆州市第二人民医院老年医学一科,湖北荆州434000

出　　处：《中国继续医学教育》2019年第9期116-118,共3页China Continuing Medical Education

摘　　要：目的探究阿奇霉素与头孢派酮钠舒巴坦钠联合用于老年肺炎患者的临床疗效。方法选取2017年8月—2018年8月在我院接受老年肺炎治疗的患者130例作为研究对象。根据药物治疗方法不同,将其分为观察组、对照组。观察组给予阿奇霉素与头孢派酮钠舒巴坦钠联合治疗,对照组给予亚胺培南与左氧氟沙星联合治疗,比较治疗前后两组患者的血液炎性因子TNF-α、IL-6、IL-8水平,以及药物疗效。结果而通过治疗1个月后,观察组患者的血液炎性因子TNF-α、IL-6、IL-8值均低于对照组,两组比较,差异具有统计学意义(P<0.05);观察组患者的治疗有效率高于对照组,两组比较,差异具有统计学意义(P <0.05)。结论在老年肺炎患者的临床治疗过程中,阿奇霉素与头孢派酮钠舒巴坦钠联合治疗可显著优化患者血液炎性因子水平,提高临床疗效。Objective To explore the clinical efficacy of Azithromycin combined with cefoperazone sodium and sulbactam sodium in the treatment of senile pneumonia. Method 130 elderly patients with pneumonia treated in our hospital from August 2017 to August 2018 were selected as the study subjects. According to the different drug treatment methods, they were divided into observation group and control group. The observation group was treated with Azithromycin combined with cefoperazone sodium and sulbactam sodium. The control group was treated with imipenem and levofloxacin. The levels of TNF-α, IL-6 and IL-8 in the blood of the two groups were compared before and after treatment. Results After one month of treatment, the blood inflammatory factors TNF-a, IL-6 and IL-8 in the observation group were lower than those in the control group. The difference between the two groups was statistically significant (P < 0.05). The treatment efficiency of the observation group was higher than that of the control group. The difference between the two groups was statistically significant (P < 0.05). Conclusion In the clinical treatment of elderly patients with pneumonia, Azithromycin combined with cefoperazone sodium and sulbactam sodium can significantly optimize the level of blood inflammatory factors and improve the clinical efficacy.

关 键 词：阿奇霉素 头孢派酮钠舒巴坦钠 联合用药 老年肺炎 炎性因子 疗效 

分 类 号：R653[医药卫生—外科学]