持续脑功能监测在新生儿缺氧缺血性脑病早期诊断中的应用效果  

Application effect of continuous brain function monitoring in early diagnosis of neonatal hypoxic ischemic encephalopathy

作　　者：罗惠玲[1] 白波[1] 黄暖潮 龚湛潮 杜小群 李广洪[1] LUO Hui-ling;BAI Bo;HUANG Nuan-chao;GONG Zhan-chao;DU Xiao-qun;LI Guang-hong(Department of Pediatrics, People′s Hospital of Huadu District of Guangzhou City in Guangdong Province, Guangzhou 510800, China)

机构地区：[1]广州市花都区人民医院儿科,广东广州510800

出　　处：《中国当代医药》2019年第7期137-139,共3页China Modern Medicine

基　　金：广东省广州市花都区科技计划项目(15-HDWS-055)

摘　　要：目的研究持续脑功能监测在早期诊断新生儿缺氧缺血性脑病中的应用效果。方法选取我院2010年1月～2018年1月收治的70例新生儿缺氧缺血性脑病患儿作为研究对象,按照电脑随机分配的方法分为对照组和观察组,每组35例。对照组采用MRI和CT检测,观察组采用持续脑功能监测,比较两组的脑损伤程度及2、6个月龄的心理功能正常率、神经功能正常率。结果两组患儿的脑功能正常率、轻度损伤率比较,差异无统计学意义(P>0.05)。观察组患儿的重度损伤率低于对照组,差异有统计学意义(P<0.05)。观察组脑功能正常患儿2、6个月龄的心理、神经功能情况均高于脑功能异常患儿,差异有统计学意义(P<0.05)。结论持续脑功能监测在早期诊断新生儿缺氧缺血性脑病中具有较高的应用价值,能够将患儿脑功能情况充分反映出来,为临床治疗提供有利依据,值得研究。Objective To study the application effect of continuous brain function monitoring in early diagnosis of neonatal hypoxic ischemic encephalopathy. Methods A total of 70 children with neonatal hypoxic ischemic encephalopathy admitted to our hospital from January 2010 to January 2018 were enrolled in the study. They were divided into the control group (n=35) and the observation group (n=35) according to computer randomization. In the control group, MRI and CT were detected, while in the observation group, continuous brain function monitoring was adopted. The degree of brain injury, the normal rates of psychological function and neurological function at 2 and 6 months were compared between the two groups. Results There was no significant difference in the normal rate of brain function or mild injury rate between the two groups (P>0.05). The severe damage rate in the observation group was lower than that in the control group, with significant difference (P<0.05). In the observation group, the psychological and neurological functions of children with normal brain function at 2 months and 6 months were higher than those with abnormal brain function, with statistical significance (P<0.05). Conclusion Continuous brain function monitoring has a high application value in early diagnosis of neonatal hypoxic ischemic encephalopathy, which can fully reflect the brain function of children and provide a favorable basis for clinical treatment. It is worthy of study.

关 键 词：持续脑功能监测 早期诊断 新生儿缺氧缺血性脑病 应用效果 

分 类 号：R729[医药卫生—儿科]