针刺结合中药周期疗法对IVF-ET失败患者不良子宫内膜容受性、胚胎种植率及妊娠率的影响  

Effect of Acupuncture Combined with TCM Cycle Therapy on Adverse Endometrial Receptivity,Embryo Implantation Rate and Pregnancy Rate in Patients with IVE-ET Failure

作　　者：高志云[1] 罗国群[1] 高修安[1] GAO Zhiyun;LUO Guoqun;GAO Xiu’an(Foshan Women and Children Hospital, Foshan 528000, China)

机构地区：[1]佛山市妇幼保健院,广东佛山528000

出　　处：《针灸临床杂志》2019年第3期31-34,共4页Journal of Clinical Acupuncture and Moxibustion

基　　金：佛山市医学类科技攻关计划;编号:2015AB00390

摘　　要：目的:研究针刺和中药周期疗法联合应用对体外受精-胚胎移植(IVF-ET)失败患者不良子宫内膜容受性、胚胎种植率和妊娠率的影响。方法:选取2016年5月—2017年5月佛山市妇幼保健院收治的行IVF-ET失败2次的患者100例,随机平均分成实验组和对照组。对照组自然等待3个月后继续常规IVF-ET治疗;实验组采用针刺联合中药周期疗法治疗3个月后再行常规IVF-ET治疗。对比分析两组患者的妊娠率、胚胎种植率、A型子宫内膜比例和子宫内膜血流指标。结果:实验组患者妊娠率、胚胎种植率和A型子宫内膜比例显著高于对照组(P <0. 05),差异具有统计学意义;实验组患者子宫内膜血流指标显著低于对照组(P <0. 05),差异具有统计学意义。结论:针刺结合中药周期疗法能显著改善IVF-ET失败患者子宫内膜容受性,增加患者再次IVF-ET的胚胎种植率和妊娠率。Objective: To study the effect of acupuncture combined with TCM cycle therapy on adverse endometrial receptivity, embryo implantation rate and pregnancy rate in patients with IVF-ET failure. Methods: 100 patients with two failures of IVF-ET from May 2016 to May 2017 were randomly divided into the study group and the control group. The control group was given IVF-ET treatment after three months natural wait for pregnacy;the study group was treated with acupuncture combined with TCM cycle therapy for three months before routine IVF-ET. The pregnancy rate, embryo implantation rate, ratio of type A endometrium and endometrial blood flow were compared between the two groups. Results: The pregnancy rate, embryo implantation rate, and type A endometrium were significantly higher in the study group than those in the control group( P <0.05). The index of endometrial blood flow was significantly lower in the study group than that in the control group( P < 0.05). Conclusion: Acupuncture combined with TCM cycle therapy can significantly improve the endometrial receptivity of the patients after IVF-ET failure, and it can increase the rate of embryo implantation and pregnancy of IVF-ET.

关 键 词：针刺 中药周期疗法 体外受精-胚胎移植 子宫内膜容受性 胚胎种植率 妊娠率 

分 类 号：R246.3[医药卫生—针灸推拿学]