加味射干麻黄汤联合西药对发作期冷哮型支气管哮喘的疗效及安全性分析  

Efficacy and safety of Jiawei Shegan Mahuang decoction combined with western medicine on cold asthmatic bronchial asthma

作　　者：杨晓华 Yang Xiaohua(Internal Medicine, Puyang County People's Hospital, Henan 457100, China)

机构地区：[1]濮阳县人民医院内科,河南457100

出　　处：《国际医药卫生导报》2019年第6期895-897,共3页International Medicine and Health Guidance News

摘　　要：目的分析加味射干麻黄汤联合西药对发作期冷哮型支气管哮喘的疗效及安全性。方法在本院接受治疗的发作期冷哮型支气管哮喘患者中选取52例作为本文的观察对象,上述患者均为2017年4月至2018年4月期间收治,以单双号分组法将所有患者分为两组,对照组和观察组患者分别给予常规西医治疗和加味射干麻黄汤联合西药治疗,对两组患者的肺功能、外周血嗜酸性粒细胞计数变化情况进行比较,统计两组患者的中医证候积分改善情况和不良反应发生情况。结果治疗后观察组患者的PEF、FEV1、EOS相比较于对照组,均明显较高,其治疗后的喘息积分、咳嗽积分、哮鸣音积分以及胸闷积分均明显低于治疗前和对照组(P<0.05);两组患者的不良反应发生率比较差异无统计学意义(P>0.05)。结论加味射干麻黄汤联合西药治疗发作期冷哮型支气管哮喘疗效可观。Objective To study the efficacy and safety of Jiawei Shegan Mahuang decoction combined with western medicine on cold asthmatic bronchial asthma. Methods A total of 52 patients with cold asthmatic bronchial asthma who were treated in our hospital from April 2017 to April 2018 were enrolled in this study, and were divided into two groups by odd and even numbers grouping. The patients in the control group were treated with conventional western medicine and the observation group were treated with Jiawei Shegan Mahuang decoction combined with Western medicine. The changes of lung function and peripheral blood eosinophil count were compared between the two groups. The improvement of TCM syndrome scores and the occurrence of adverse reactions were recorded. Results PEF, FEV1, and EOS in the observation group were significantly higher than those in the control group after treatment, and the wheeziness score, cough score, wheezing rale score, and chest tightness score in the observation group after treatment were significantly lower than those before treatment and in the control group (P<0.05). There was no statistically significant difference in the incidence of adverse reactions between the two groups (P>0.05). Conclusion Jiawei Shegan Mahuang decoction combined with western medicine is effective in treating cold asthmatic bronchial asthma.

关 键 词：发作期冷哮型支气管哮喘 加味射干麻黄汤 西药 

分 类 号：R562.25[医药卫生—呼吸系统]