老年高血压患者血压昼夜节律对左室肥厚的影响  

Relationship between blood pressure circadian rhythm and left ventricular hypertrophy in elderly patients with essential hypertension

作　　者：侯晓林[1] 彭羽[1] 黄久荣[1] 喻蓉[1] 巴桑[1] 杨喜耕[1] HOU Xiaolin;PENG Yu;HUANG Jiurong;YU Rong;BA Sang;YANG Xigeng(Sichuan Academy of Medical Science,Sichuan Provincial People’s Hospital,Chengdu 610072,China)

机构地区：[1]四川省医学科学院.四川省人民医院,四川成都610072

出　　处：《西部医学》2019年第3期374-377,共4页Medical Journal of West China

基　　金：四川省卫计委科研项目(080372)

摘　　要：目的研究老年高血压患者的血压昼夜节律变化对左室肥厚的影响。方法选取我院126例高血压患者,根据心脏彩超提示左室肥厚情况分为肥厚组(n=52例)和非肥厚组(n=74例)。比较两组动态血压指标及血压变异性,进行多因素分析探讨血压变异性对左室肥厚的影响。结果高血压肥厚组24h平均收缩压(24hSBP)、白天平均收缩压(dSBP)、夜间平均收缩压(nSBP)、24h收缩压标准差(24hSSD)、24h舒张压标准差(24hDSD)、白天收缩压标准差(dSSD)、夜间收缩压标准差(nSSD)均高于非肥厚组,差异有统计学意义(P<0.05)。Logistic回归分析显示,24h SBP与dSSD、nSSD为左室肥厚的独立危险因素(P<0.05)。结论老年高血压患者的24h SBP与dSSD、nSSD是影响左室肥厚的独立危险因素,平稳控制血压对防止左室肥厚的发生有一定影响。Objective To explore the relationship between blood pressure variability (BPV) and left ventricular hypertrophy in patients with essential hypertension.Methods 126 patients of essential hypertension were divided to left ventricular hypertrophy (LVH) group (n=52) and non-left ventricular hypertrophy group (non-LVH,n=74).Parameters of ambulatory blood pressure monitoring and BPV parameters differences were compared between them.Results 24hSBP,dSBP,nSBP,24 hSSD,24hDSD,dSSD and nSSD in LVH group were higher than non-LVH group(P<0.05).Logistic regression analysis showed that 24h SBP,dSSD and NSSD were the independent risk factors of left ventricular hypertrophy.Conclusions 24h SBP,dSSD and NSSD of old essential hyperternsion patients are independent risk factors of LVH.Stably controlling of blood pressure has a certain effect on delaying the occurrence of LVH.

关 键 词：老年高血压 动态血压 左室肥厚 昼夜节律 

分 类 号：R544.11[医药卫生—心血管疾病]