206例男性尖锐湿疣复发的危险因素分析  

Analysis of risk factors for 206 cases of recurrent condylomaacuminatum

作　　者：蔡光辉[1] 王是[1] CAI Guanghui;WANG Shi(Department of Dermatology, Huangshi Central Hospital, The Affiliated Hospital of Hubei Polytechnic University, Edong Health Care Group, Huangshi435000, Hubei, China)

机构地区：[1]鄂东医疗集团黄石市中心医院(湖北理工学院附属医院)皮肤科,湖北黄石435000

出　　处：《中国性科学》2019年第3期130-132,共3页Chinese Journal of Human Sexuality

摘　　要：目的探讨206例男性尖锐湿疣复发的危险因素分析的危险因素,为临床防治提供参考。方法选取2015年12月至2017年12月鄂东医疗集团黄石市中心医院(湖北理工学院附属医院)诊治的男性尖锐湿疣患者206例作回顾性分析。其中复发118例,复发率57.3%,不复发88例。对患者的年龄、文化程度、嗜酒、吸烟、熬夜、性伴侣、安全套使用、皮损数量、包皮过长、睡眠时间等资料进行调查统计,并采用单因素及多因素分析影响男性尖锐湿疣复发的危险因素。结果单因素分析显示,两组(复发、未复发)人群在文化程度、年龄、吸烟、嗜酒等方面对比,差异无统计学意义(P>0.05);但复发组在性伴侣2个及以上、熬夜、皮损数量多发、未使用安全套、T细胞亚群异常方面均多于未复发组,差异具有统计学意义(P<0.05)。多因素分析显示,性伴侣2个及以上、熬夜、皮损数量多发、未使用安全套、T细胞亚群异常均为尖锐湿疣复发的独立危险因素。结论男性尖锐湿疣复发的危险因素分析包括性伴侣2个及以上、熬夜、皮损数量多发、未使用安全套、T细胞亚群异常等,临床上建议针对上述因素做出针对性防治措施。Objective To explore the risk factors of recurrent condylomaacuminata( CA) in 206 cases, in order to provide reference for the prevention and treatment of CA. Methods 206male patients with CA treated in Huangshi Central Hospital from December 2015to December 2017were selected for retrospective analysis. Among them, 118 cases recurred, the recurrence rate of 57. 3%. The age, education level, alcohol consumption, smoking, staying up late, number of sexual partners, condom use, skin lesions, redundant prepuce and sleep time were investigated. The risk factors for recurrence of male condylomaacuminatum were analyzed by univariate and multivariate analysis. Results According to univariate analysis,there was no significant difference in education level, age, smoking andalcohol consumption ( P > 0. 05 ). The incidences of having 2 or more sexual partners, staying up late, large number of lesions, not using condoms and abnormal T cell subsets in therecurrence group were higher than those of the non-recurrence group, all with statistically significant differences ( P < 0. 05 ). Multivariate analysis showed that having 2 or more sexual partners,staying up late, large number of lesions, not using condoms and abnormal T cell subsets were all independent risk factors for the recurrence of CA. Conclusions The risk factors for recurrence of male CA include having 2 or more sexual partners,staying up late, large number of lesions, not using condoms and abnormal T cell subsets, so targeted interventions should be taken in clinical.

关 键 词：男性尖锐湿疣 复发 危险因素分析 多因素分析 

分 类 号：R759[医药卫生—皮肤病学与性病学]