神经病理性疼痛动物模型的制备与评价方法  

The Establishment and Evaluation of Animal Models of Neuropathic Pain

作　　者：武亚茹 常可欣 贾庆忠[1] WU Ya-ru;CHANG Ke-xin;JIA Qing-zhong(Hebei Medical University,Shijiazhuang,050017,China)

机构地区：[1]河北医科大学,石家庄050017

出　　处：《神经药理学报》2017年第5期15-20,共6页Acta Neuropharmacologica

基　　金：国家自然科学基金资助项目(No.30970659);河北省高层次人才项目(No.2014038).

摘　　要：神经病理性疼痛是由于躯体感觉系统的损伤或疾病所导致的疼痛。该文综述了外周神经损伤或带状疱疹、糖尿病、癌症等疾病所致的神经病理性疼痛动物模型及行为学评价方法。Neuropathic pain can be defined as “pain arising as a direct consequence of a lesion or disease affecting the somato-sensory system”.This article reviews animal models of neuropathic pain induced by peripheral nerve injury,herpes zoster,diabetes and cancer and its evaluation methods.

关 键 词：神经病理性疼痛 动物模型 痛觉超敏 痛觉过敏 

分 类 号：R965[医药卫生—药理学]