空间偏移拉曼光谱技术的发展及应用  

Development and Application of Spatially Offset Raman Spectroscopy

作　　者：朱婷 刘洋[2,3] 吴军[2,4] 王恩亮[1] 薛峰 ZHU Ting;LIU Yang;WU Jun;WANG En-liang;XUE Feng(Anhui Xihua University, Hefei 230088, China;Hefei Institutes of Physical Science, Chinese Academy of Sciences, Hefei 230031, China;Institute of Intelligent Machines, Chinese Academy of Sciences, Hefei 230031, China;Anhui Institute of Optics and Fine Mechanics, Chinese Academy of Sciences, Hefei 230031, China;Anhui Sanlian University, Hefei 230601, China)

机构地区：[1]安徽新华学院,安徽合肥230088 [2]中国科学院合肥物质科学研究院,安徽合肥230031 [3]中国科学院合肥智能机械研究所,安徽合肥230031 [4]中国科学院安徽光学精密机械研究所,安徽合肥230031 [5]安徽三联学院,安徽合肥230601

出　　处：《光谱学与光谱分析》2019年第4期997-1004,共8页Spectroscopy and Spectral Analysis

基　　金：国家自然科学基金项目(41505020);国家级质量工程项目(2013sjjdg01)资助

摘　　要：传统拉曼光谱只能探测样品的表层信息,或者只能穿透透明的表层探测样品内部,对多层不透明或不透明包装的样品检测则不适用了,比如搜索隐蔽的爆炸物、识别有包装的假药、无损检测骨骼疾病等。空间偏移拉曼光谱(SORS)技术是一种新型光谱检测技术,能够非侵入不透明包装或表层直接获得样品内部深层特征信息,这一技术的出现解决了上述的难题。首先详细介绍了SORS技术的工作原理:其根本原理在于光子迁移理论,其系统激光光源的入射焦点与光谱系统中收集透镜的焦点在待测样品表层空间上偏移一定的距离ΔS。当激光入射到待测样品表层时,表层样品被激发或散射出宽带荧光,其中有一部分散射光将到达样品内部,样品内部深层处产生的拉曼散射光子相比于样品表层的光子在散射过程中更易于横向迁移,经多次散射后返回样品表层被光谱仪器接收系统收集。到达样品内部不同深度ΔH的散射光返回表层后的位置距离激光光源入射点在样品表层上有不同的偏移距离ΔS。当空间偏移距离ΔS=0时,激光光源入射点与拉曼光谱收集点重合,此处激发的光子密度最大,系统收集到的拉曼光谱信号大部分来自样品表层,样品深层拉曼信号被淹没;当空间偏移距离ΔS≠0时,光谱仪器收集到的拉曼光谱信号中来自表层的信号衰减很快,来自样品深层的信号衰减较慢,使得更深层的拉曼散射光子比重变大,从而实现光谱分离,再结合多元数据分析方法可以获得样品内部不同深层次的拉曼光谱,即空间偏移拉曼光谱。该技术具有很好抑制表层物质拉曼光谱和荧光光谱干扰的能力,特别适用于隐蔽在不透明包装材料下的物质拉曼光谱的提取,从而快速、非侵入地对目标物成分进行鉴定。其次介绍了SORS技术的特点。SORS技术是拉曼光谱的衍生技术,具备拉曼光谱技术的制样简单、�The traditional Raman spectroscopy can only detect the surface information of the sample, or can only through the transparent surface detect the inner information of the sample, and it has same problems to get information of multilayer opaque sample or opaque packaging sample, such as searching for hidden explosives, identifying fake medicine with opaque package and non-invasive detection of bone disease, etc.. Spatially offset Raman Spectroscopy(SORS) is a new type of spectral detection technique, which can get information from opaque package non-invasively or gain information through surface layer to inner of the sample directly. This technology solves the problems mentioned above. Firstly, this paper introduced the principle of SORS in detail. The fundamental principle lies in the theory of photon migration. Between the focus point of the incident laser light source and the focus point of the collect lens there is a certain spatial distance offset ΔS from surface of the sample. When the laser light incident into the surface of sample, it will be stimulated or scatter broadband fluorescence by the surface of sample. One part of scattered light will reach to the inner of sample, and the photons of Raman scattered light from inner sample is easier to migrate than the photons of the surface of sample. The photons of Raman scattered light are returned to the surface of sample and collected by optical system after multiple scattering. Scattered light from different depths ΔH have different spatial distance offset ΔS after returning to the surface of sample.When the spatial distance offset ΔS is zero, the focus point of the incident laser light and the focus point of the collect lens are coincided where the density of photons is maximum, and the Raman signal collected by optical system are mostly from the surface of sample, and Raman signal of inner sample is submerged. When the spatial distance offset ΔS is not zero, the Raman signal from the surface of sample collected by optical system is attenuated quickly,

关 键 词：空间偏移拉曼光谱 深层检测 非侵入检测 化工医疗 

分 类 号：O433.4[机械工程—光学工程]