痰热清注射液联合参附注射液治疗老年重症肺炎的临床效果  

Clinical effect of Tanreqing Injection combined with Shenfu Injection in the treatment of senile severe pneumonia

作　　者：郭玉梅[1] 庚俐莉[1] 舒姣洁 张芸[1] 徐显楠 刘昊 臧士国 GUO Yu-mei;GENG Li-li;SHU Jiao-jie;ZHANG Yun;XU Xian-nan;LIU Hao ZANG Shi-guo(ICU of Emergency,Dalian Central Hospital,Liaoning Province,Dalian 116033,China)

机构地区：[1]大连市中心医院急诊ICU,辽宁大连116033

出　　处：《中国当代医药》2019年第8期151-154,共4页China Modern Medicine

基　　金：国家自然科学基金资助项目(81301721)

摘　　要：目的探讨痰热清注射液联合参附注射液治疗老年重症肺炎的临床效果。方法选取2016年6月～2018年6月我院收治的老年重症肺炎患者98例为研究对象,采用随机数字表法,将患者分为对照组和观察组,每组49例。对照组患者采用抗感染、化痰、辅助通气、营养支持等常规西医治疗,观察组在对照组基础上加用痰热清注射液和参附注射液进行治疗。比较两组患者的治疗总有效率、死亡率、重症监护室(ICU)停留时间、住院日和住院费用,以及血常规和血气分析改善情况。结果观察组的治疗总有效率高于对照组,死亡率低于对照组,ICU停留时间和住院日短于对照组,住院费用低于对照组,差异有统计学意义(P<0.05);治疗后,两组患者的白细胞(WBC)均较治疗前降低,且观察组WBC低于对照组,差异有统计学意义(P<0.05);治疗后,两组患者的血小板(PLT)、动脉血氧分压(PaO_2)、血氧饱和度(SaO_2)、氧合指数(PaO_2/FiO_2)均高于治疗前,且观察组高于对照组,差异有统计学意义(P<0.05)。结论在常规西医治疗基础上,加用痰热清注射液和参附注射液可显著提高老年重症肺炎的治疗效果,降低死亡率,缩短病程,值得临床推广。Objective To investigate the clinical effect of Tanreqing Injection combined with Shenfu Injection in the treatment of senile severe pneumonia. Methods All of 98 elderly patients with severe pneumonia treated in our hospital from June 2016 to June 2018 were selected as the study subjects. The patients were divided into the control group and observation group according to the random number table method,with 49 cases in each group. The patients in the control group were treated with routine western medicine such as anti-infection,phlegm-resolving,assisted ventilation and nutritional support. The observation group was treated with Tanreqing Injection and Shenfu Injection on the basis of the control group. The total effective rate of treatment,mortality rate,residence time in intensive care unit (ICU),hospitalization day and hospitalization cost,blood routine and blood gas analysis were compared between the two groups. Results The total effective rate in the observation group was higher than the control group,the mortality rate was lower than the control group,the residence time in ICU and the hospitalization day were shorter those of the control group,and the hospitalization cost was less than that in the control group,and the differences were significant (P<0.05). After treatment,the white blood cell (WBC) in the two groups were lower than those before treatment,and the WBC in the observation group was lower than that of the control group,and the differences were statistically significant (P<0.05). The platelet (PLT),arterial partial pressure of oxygen (PaO2),blood oxygen saturation (SaO2),oxygenation index (PaO2/FiO2) in the two groups were higher than those before treatment,and the above-mentioned indexes in the observation group was higher than those in the control group,and the differences were statistically significant (P<0.05). Conclusion On the basis of conventional western medicine treatment,the addition of Tanreqing Injection and Shenfu Injection can significantly improve the treatment effect of senile pat

关 键 词：痰热清注射液 参附注射液 老年 重症肺炎 

分 类 号：R563.19[医药卫生—呼吸系统]