脾脏大小对免疫性血小板减少症患者脾切除术后短期疗效的影响  

Effect of spleen size on short-term efficiency after splenectomy in patients with immune thrombocytopenia(ITP)

作　　者：王健铭 梁晋尧 易鑫 万顺源 罗诗樵[1] WANG Jianming;LIANG Jinyao;YI Xin;WAN Shunyuan;LUO Shiqiao(Department of Hepatobiliary Surgery,the First Affiliated Hospital of Chongqing Medical University,Chongqing400016,China)

机构地区：[1]重庆医科大学附属第一医院肝胆外科,重庆400016

出　　处：《中国医药科学》2019年第5期18-21,共4页China Medicine And Pharmacy

基　　金：重庆市基础与前沿研究计划项目(cstc2013jcyjA10105)

摘　　要：目的探讨脾脏大小对免疫性血小板减少症(ITP)患者脾切除术后短期疗效的影响。方法选取2013年4月～2017年10月期我院行脾切除术治疗的67例ITP患者,根据患者脾脏体积指数分为正常组(<600cm^3)与脾大组(> 600cm^3),对两组患者的短期起效率(30d起效率)的比较采用χ~2检验。结果 67例患者中,28例脾脏大小正常,39例脾脏增大。脾大组短期起效率76.92%高于正常组短期起效率53.57%,差异有统计学意义(P <0.05)。结论脾切除术是一种治疗ITP安全、有效的治疗方法。脾脏大小是一项能有效预测ITP患者脾切除短期疗效的指标。Objective To explore the effect of spleen size on short-term efficiency after splenectomy in patients with immune thrombocytopenia(ITP). Methods Sixty-seven ITP patients who underwent splenectomy in our hospital from April 2013 to October 2017 were selected and divided into normal group(< 600cm3 )and splenomegaly group(> 600cm3 )according to their spleen volume index.χ^2 test was used to compare the short-term efficiency(30 days efficiency)between the two groups. Results Of 67 patients,28 had normal spleen size and 39 had enlarged spleen.The short-term efficiency of splenomegaly group was(76.92%)higher than the normal group(53.57%),the difference was statistically significant(P<0.05). Conclusion Splenectomy is a safe and effective treatment for ITP.Spleen size is an effective predictor of short-term outcome of splenectomy in ITP patients.

关 键 词：免疫性血小板减少症 脾切除术 脾脏大小 脾肿大 

分 类 号：R657.6[医药卫生—外科学]