小反刍兽疫病毒分子生物学及其疫苗研究进展  

MOLECULAR BIOLOGY AND VACCINE DEVELOPMENT OF PESTE DES PETITS RUMINANTS VIRUS

作　　者：董丹丹 刘腾[1] 缪秋红[1] 朱杰[1] 张莉 殷冬冬[1] 唐井玉 李传峰 陈宗艳[1] 刘光清[1] DONG Dan-dan;LIU Teng;MIAO Qiu-hong;ZHU Jie;ZHANG Li;YIN Dong-dong;TANG Jing-yu;LI Chuan-feng;CHEN Zong-yan;LIU Guang-qing(Shanghai Veterinary Research Institute,CAAS,Shanghai200241,China;College o f Anim al Science and Technology,Anhui AgriculturalUniversity,Hefei 230036,China)

机构地区：[1]中国农业科学院上海兽医研究所,上海200241 [2]安徽农业大学动物科技学院,合肥230036

出　　处：《中国动物传染病学报》2019年第1期110-118,共9页Chinese Journal of Animal Infectious Diseases

基　　金：国家重点研发计划项目(2016YFD0500108);国家自然科学基金项目(31502068);上海市科技兴农重点攻关项目(2016043);公益性农业科研专项(201303046);中央级公益性科研院所基本科研业务费专项(2016JB01)

摘　　要：小反刍兽疫病毒属于副黏病毒科、麻疹病毒属,主要感染山羊、绵羊、野生小反刍兽,临床症状以发热、肺炎、腹泻及呼吸道和消化道黏膜炎症为主要特征。目前小反刍兽疫在世界范围内广泛传播,给畜牧业造成了严重经济损失。加强对小反刍兽疫病毒的致病机理和疫苗研究,对于防控小反刍兽疫具有重要意义。本文对近年来小反刍兽疫病毒及其疫苗研究领域的进展进行了综述与展望。Peste des petits ruminants virus (PPRV) is a member of the genus Morbillivims belonging to the family Paramyxoviridae. PPRV mainly infects goats, sheep and wild small ruminant animals. The main signs of Peste des petits ruminants(PPR) are fever, pneumonia, profuse diarrhea, and inflammation of the mucous membrane of the respiratory and digestive tracts. The disease is now spreading widely around the world and has caused serious economic losses to the livestock industry. Therefore, it is of great importance to strengthen the research of the etiology, pathogenesis and vaccine of PPRV. This article reviews and prospects the progress in these areas in recent years.

关 键 词：小反刍兽疫病毒 疫苗 进展 

分 类 号：S852.659.5[农业科学—基础兽医学]