多囊卵巢综合征不孕患者中医证候分布规律研究  

Distribution of TCM Syndromes in infertility patients with polycystic ovary syndrome

作　　者：方群英 吴丽敏[1] 孙秀英 方朝辉[3,4] FANG Qun-ying;WU Li-min;SUN Xiu-ying;FANG Chao-hui(First Affiliated Hospital of USTC,Hefei,Anhui,230001,China;Anhui University of Traditional Chinese Medicine,Hefei,Anhui,230001,China;First Affiliated Hospital of Anhui University of Traditional Chinese Medicine,Hefei,Anhui,230038,China;Institute of Didbetes Prevention and Treatment of Traditional Chinese Medicine,Anhui Academy of Traditional Chinese Medicine,Hefei,Anhui,230038,China)

机构地区：[1]中国科学技术大学附属第一医院(安徽省立医院),安徽合肥230001 [2]安徽中医药大学研究生院,安徽合肥230038 [3]安徽中医药大学第一附属医院,安徽合肥230038 [4]安徽省中医药科学院中医药糖尿病防治研究所,安徽合肥230038

出　　处：《时珍国医国药》2018年第12期3067-3070,共4页Lishizhen Medicine and Materia Medica Research

基　　金：国家自然科学基金面上项目(81373671).

摘　　要：目的探讨多囊卵巢综合征不孕患者不同中医证候分布规律。方法参照多囊卵巢综合征不同中医证候分布规律的相关文献,制定多囊卵巢综合征不孕患者调查表,回顾调查分析216例多囊卵巢综合征不孕患者,对其中医症状、体重指数等数据进行采集。通过频数分析、聚类分析归类分析,归纳出多囊卵巢综合征不孕患者中医证候分布规律。结果通过频数分析和聚类分析得出5个中医证型,分别为脾虚型(76例,35. 19%)、痰湿型(68例,31. 48%)、肝郁型(33例,15. 28%)、肾虚型(24例,11. 11%)、其他型(15例,6. 94%)。脾虚型和痰湿型患者肥胖程度和糖代谢异常程度较重。结论多囊卵巢综合征不孕患者中医证候可聚为脾虚型、痰湿型、肝郁型、肾虚型、其他型五大类型,多虚实夹杂,以脾虚、痰湿为主。Objective To explore the distribution regularity of different TCM syndromes in infertility patients with polycystic ovary syndrome( PCOS). Methods Referring to the relevant literature on the distribution of different TCM syndromes of polycystic ovary syndrome,a questionnaire for infertility patients with polycystic ovary syndrome was developed. 216 infertility patients with polycystic ovary syndrome treated in outpatient clinic of reproductive center of Anhui Provincial Hospital from September 2016 to December 2017 were retrospectively investigated and analyzed,and their TCM symptoms and body mass index were compared.Data collection. Through frequency analysis,cluster analysis and classification analysis,the distribution regularity of TCM syndromes in infertility patients with polycystic ovary syndrome was concluded. Results Six TCM syndromes were identified by frequency analysis and cluster analysis,which were spleen deficiency type( 76 cases,35. 19%),phlegm-dampness type( 68 cases,31. 48%),liver depression type( 33 cases,15. 28%),kidney deficiency type( 24 cases,11. 11%) and other types( 15 cases,6. 94%). Patients with spleen deficiency and phlegm dampness type had higher obesity and abnormal glucose metabolism.Conclusion The TCM syndromes of infertility patients with polycystic ovary syndrome can be classified into five types: spleen deficiency,phlegm-dampness,liver depression,kidney deficiency and other types. The main syndromes are spleen deficiency and phlegm-dampness.

关 键 词：多囊卵巢综合征 中医证候 聚类分析 讨论 

分 类 号：R271.9[医药卫生—中西医结合]