ClC-3在子宫内膜异位症中的研究进展  

Research progress of Cl C-3 in endometriosis

作　　者：皮亚男 曹婧 侯爽[1] 周碎央 邱晓红[1] Pi Yanan;Cao Jing;Hou Shuang;Zhou Suiyang;Qiu Xiaohong(Department of Gynecology and Obstetrics,The Second Affiliated Hospital of Harbin Medical University,Harbin 150001,China)

机构地区：[1]哈尔滨医科大学附属第二医院妇产科,150001

出　　处：《中国医师杂志》2019年第2期319-320,F0003,共3页Journal of Chinese Physician

摘　　要：氯离子通道3(Cl C-3)是由CLCN3基因编码,电压门控成员Cl2通道超家族的一员,并涉及到调节电活动、细胞体积、增殖、迁移、侵袭、凋亡和细胞内p H,成为目前研究的热点。近年来Cl C-3在妇科疾病中的研究日益增多,本文将对Cl C-3与妇科良恶性疾病,尤其是对Cl C-3与子宫内膜异位症发生发展相关的研究进展进行综述。Chloride Channel-3 (ClC-3) is a member of the Cl2 channel superfamily, which is encoded by CLCN3 gene. It involves regulating electrical activity, cell volume, proliferation, migration, invasion, apoptosis and intracellular pH, which have become a hot spot of current research. In recent years, the research of ClC-3 in gynecological diseases is increasing day by day. This article will review the research progress of ClC-3 and benign and malignant gynecological diseases, especially the relationship between ClC-3 and the occurrence and development of endometriosis.

关 键 词：子宫内膜异位症 氯化物通道 细胞运动 综述 

分 类 号：R711.71[医药卫生—妇产科学]