自血疗法治疗哮喘病疗效的系统评价及Meta分析  

Systematic Evaluation and Meta-analysis of the Efficacy of Autohemotherapy in the Treatment of Asthma

作　　者：陈晓东[1] 居尚 童画 苏克雷[2] 谌晓莉[2] 张业清[2] CHEN Xiaodong;JU Shang;TONG Hua;SU Kelei;ZHAN Xiaoli;ZHANG Yeqing(Clinical Medical School of Traditional Chinese and Western Medicine,Nanjing University of Chinese Medicine,Nanjing 210046,China;Jiangsu Province Hospital on Integrated of Chinese and Western Medicine,Nanjing 210028,China)

机构地区：[1]南京中医药大学中西医临床医学院,南京210046 [2]江苏省中西医结合医院,南京210028

出　　处：《长春中医药大学学报》2019年第1期58-61,共4页Journal of Changchun University of Chinese Medicine

基　　金：国家自然科学基金青年基金项目(81503573);江苏省科技项目合同(BK20161079)

摘　　要：目的通过对国内外发表的关于自血疗法治疗哮喘病的随机对照试验进行系统评价及meta分析,定性判定自血疗法治疗哮喘病的有效性。方法文献检索CNKI、万方、维普、中国生物医学文献服务系统、Pubmed及Cochrane Library数据库,找到相关文献,导入Noteexpress系统,经过查重筛选、分析提取等纳入相关随机对照试验。采用Revman 5.3系统对纳入文献进行质量评价及meta分析。结果共导入文献216篇,纳入11篇,合计受试者797人。Meta分析结果示,自血疗法对比西药疗法,疗效明显(P <0.01);自血疗法+其它药物疗法,有效率明显高于药物单独治疗(P <0.01);自血疗法+针灸理疗/+药物治疗,有效率明显高于只用药物或针灸理疗治疗(P <0.01)。结论自血疗法独用或联合其它疗法治疗哮喘病疗效明显,具有一定科学意义及临床价值。Objective To evaluate the efficacy and safety of autohemotherapy in the treatment of asthma by systematically evaluating meta-analysis of randomized controlled trials published in China and abroad on the treatment of asthma by autohemotherapy. Methods Document search CNKI, Wanfang, Vip, China Biomedical Literature Service System, Pubmed, and Cochrane Library database, import Noteexpress system, check-heavy screening, analysis, etc. were included in relevant randomized controlled trials. The meta-analysis of the included literature was performed using the Revman 5.3 system. Results A total of 216 articles were imported and 11 articles were included. The total number of subjects was 797. The results of meta analysis showed that autohemotherapy was more effective than western medicine (P<0.01);autologous blood therapy + other drug therapy was significantly more effective than drug alone (P<0.01);autologous blood therapy + acupuncture therapy/+ Drug treatment was significantly more effective than either drug alone or acupuncture physiotherapy (P<0.01). Conclusion The efficacy of autohemotherapy alone or in combination with other therapies for treating asthma is obvious. It has scientific significance and clinical value.

关 键 词：自血疗法 哮喘 META分析 

分 类 号：R255.6[医药卫生—中医内科学]