皮肤结核病研究进展  

Cutaneous tuberculosis

作　　者：陈燕清 王洪生 Chen Yanqing;Wang Hongsheng(Laboratory of My cobacteriology. Hospital for Skin Diseases,Chinese Academy of Medical Sciences and PekingUnion Medical College,Nanjing 210042,China)

机构地区：[1]中国医学科学院北京协和医学院皮肤病医院分枝杆菌实验室,南京210042

出　　处：《中华皮肤科杂志》2019年第3期215-219,共5页Chinese Journal of Dermatology

基　　金：江苏省科技计划项目(BE2018619);中国医学科学院医学与健康科技创新工程项目(2017-I2M-B&R-14).

摘　　要：皮肤结核病由结核杆菌复合群引起,临床表现因感染途径、宿主免疫力等因素差异而呈多样性。传统的实验室诊断方法如抗酸染色直接镜检、培养、病理检查等在皮肤结核诊断和治疗中起重要作用,近年来以核酸扩增技术为代表的系列检测技术的发展为其临床精准诊断和治疗提供了重要保障本文将综述皮肤结核病的病因与发病机制、临床表现、实验室检查和治疗进展.Cutaneous tuberculosis is an infectious disease caused by Mycobacterium tuberculosis complex.Its clinical manifestations vary with infection route,host immunity,etc.Traditional laboratory examinations,including acid-fast staining followed by direct microscopy,cultivation,histopathological examination and so on,still play important roles in the diagnosis and treatment of cutaneous tuberculosis.Development of a series of laboratory techniques represented by nucleic acid amplification tests provides significant support for accurate clinical diagnosis and treatment in recent years.This review summarizes advances in the etiology,pathogenesis,clinical manifestations,laboratory examinations and treatment of cutaneous tuberculosis.

关 键 词：结核 皮肤 诊断 临床方案 

分 类 号：R529.4[医药卫生—内科学]