2008—2015年天津市HIV-1新近感染特征及相关因素分析  

The characteristics of recent HIV-1 infection and associated factors in Tianjin

作　　者：宁铁林[1] 郭燕[1] 郑敏娜[1] 柏建芸[1] 赵璇[1] 周宁[1] 龚卉[1] 程绍辉[1] Ning Tielin;Guo Yan;Zheng Minna;Bai Jianyun;Zhao Xuan;Zhou Ning;Gong Hui;Cheng Shaohui(Department of AIDS/STD Prevention and Control, Tianjin Centers for Disease Prevention and Control, Tianjin 300011, China)

机构地区：[1]天津市疾病预防控制中心性病艾滋病预防控制室,300011

出　　处：《中华预防医学杂志》2019年第3期323-326,共4页Chinese Journal of Preventive Medicine

基　　金：天津市卫生行业重点攻关项目(14KG119).

摘　　要：对2008—2015年天津市HIV感染者和艾滋病患者(HIV/AIDS)报告病例进行新近感染判定,分析HIV-1新近感染相关因素。2008—2015年天津市男男同性性传播占全部HIV-1新近感染者比例由37.7%上升至83.7%。≤30岁(OR=1.53,95%CI:1.30~1.79)、汉族(OR=1.40,95%CI:1.02~1.91)、高中(OR=1.28,95%CI:1.05~1.56)和大学(OR=1.23,95%CI:1.00~1.50)学历、学生(OR=1.79,95%CI:1.28~2.51)感染者中为新近感染的可能性较高;通过自愿咨询检测(VCT)(OR=2.58,95%CI:2.026~3.29)、性病门诊(OR=2.02,95%CI:1.51~2.71)、男男性行为人群(MSM)专题调查(OR=2.88,95%CI:2.33~3.58)和无偿献血者筛查(OR=2.64,95%CI:1.84~3.79)发现的感染者为新近感染的可能性较高。The newly reported HIV infected cases was collected, and HIV blood samples were detected to identify recent HIV infection in Tianjin during 2008-2015. Factors associated with HIV-1 infection were analyzed by the univariate and multivariate unconditional logistic regression. The recent HIV-1 infection proportion of homosexuals increased from 37.70% in 2008 to 83.68% in 2015. Those cases who aged ≤30 years (OR=1.53, 95%CI: 1.30-1.79), in han ethnic group (OR=1.40, 95%CI: 1.02-1.91), students (OR=1.79, 95%CI: 1.28-2.51) were more likely to be recent infected. The cases who had a high school education (OR=1.28, 95%CI: 1.05-1.56) or collage education (OR=1.23, 95%CI: 1.00-1.50) were more likely to be recent infected than those who had a primary school education. Compared with patients identified by hospitals, the recent HIV infections were more likely to be found through voluntary counseling and testing (VCT), STD outpatients, men who have sex with men (MSM) investigation and unpaid blood donors. Homosexual transmission has become the major route of HIV-1 recent infection in Tianjin.

关 键 词：HIV HIV血清阳性 流行病学 BED捕获酶联免疫方法 新近感染 

分 类 号：R512.91[医药卫生—内科学]