Marchiafava-Bignami病MRI诊断及鉴别诊断的研究进展  

Recent advances in MR imaging in diagnosis and differential diagnosis of Marchiafava-Bignami disease

作　　者：王佳琦 李胜[1] Wang Jiaqi;Li Sheng(Department of Neurology, First Affiliated Hospital of Dalian Medical University, Dalian 116011, China)

机构地区：[1]大连医科大学附属第一医院神经内科,大连116011

出　　处：《中华神经医学杂志》2019年第3期312-315,共4页Chinese Journal of Neuromedicine

摘　　要：Marchiafava-Bignami病(MBD)是一种罕见的、以胼胝体脱髓鞘和坏死为主要病理特征的慢性酒精中毒相关性疾病。早期识别和治疗有助于改善其预后。由于该病缺乏特异性的临床表现,尤其在急性期易与某些疾病相混淆,确诊有赖于影像学检查。本文就近年来有关MRI在MBD诊断及鉴别诊断中的应用进展进行综述,以期为MBD的早期诊治提供指导和借鉴。Marchiafava-Bignami disease (MBD) is a rare disorder associated with chronic alcoholism characterized pathologically by demyelination and necrosis of the corpus callosum. Early recognition and treatment may provide a favorable outcome. Since it has no specific symptoms and signs, and may mimic several disorders, especially in its acute phase, neuroimaging is essential to confirm the diagnosis. This review highlights the pivotal role of MR imaging in the diagnosis and treatment, and differential diagnosis of MBD.

关 键 词：MARCHIAFAVA-BIGNAMI病 MRI 诊断 鉴别诊断 

分 类 号：R445.2[医药卫生—影像医学与核医学] R595.6[医药卫生—诊断学] R747.9[医药卫生—临床医学]