肥胖伴阻塞性睡眠呼吸暂停低通气综合征患者的睡眠及情绪状况分析  

Analysis on sleep and emotional symptoms in obese patients with obstructive sleep apnea hypopnea syndrome

作　　者：马萍[1] 温金峰 廖继武[1] 王丝丝[1] 潘集阳[1] MA Ping;WEN Jin-feng;LIAO Ji-wu;WANG Si-si;PAN Ji-yang(Department of Psychiatry and Sleep Disorders Center, the Affiliated Hospital y Jinan University, Guangzhou 510630, Guangdong, China)

机构地区：[1]暨南大学附属第一医院精神医学科睡眠医学中心,广东广州510630 [2]广东三九脑科医院心理行为医学科睡眠医学中心,广东广州510510

出　　处：《广东医学》2019年第4期459-462,共4页Guangdong Medical Journal

摘　　要：目的探讨肥胖伴阻塞性睡眠呼吸暂停低通气综合征(OSAHS)患者主观睡眠质量、情绪及心理健康水平。方法根据多导睡眠监测的呼吸暂停低通气指数(AHI),将肥胖患者分为OSAHS组103例及对照组59例,再将OSAHS组分为重度组58例及轻中度组45例,采用匹兹堡睡眠质量指数量表(PSQI)、Epworth嗜睡量表(ESS)、抑郁自评量表(SDS)、焦虑自评量表(SAS)和症状自评量表(SCL-90)进行评估,分析各组之间上述量表评分的差异。结果 OSAHS组PSQI、ESS、SAS、SDS评分均比对照组高,OSAHS重度组ESS、SDS、SAS评分均比轻中度组高,差异有统计学意义(P<0.05);SCL-90评分在OSAHS组与对照组比较及重度组与轻中度组比较中,除强迫状态差异无统计学意义外,其余各因子及总分差异均有统计学意义(P<0.05)。结论肥胖伴OSAHS患者主观睡眠质量、白天过度思睡、抑郁、焦虑情绪及心理健康水平均较无OSAHS的肥胖患者差,且随OSAHS程度的加重而加重。Objective To investigate the subjective sleep quality, mood and mental health level of obese patients with obstructive sleep apnea hypopnea syndrome(OSAHS). Methods According to the apnea hypopnea index(AHI) monitored by polysomnography, obese patients were divided into OSAHS group(103 patients) and control group(59 patients). OSAHS group was further divided into severe group(58 patients) and mild-moderate group(45 patients). The Pittsburgh Sleep Quality Index(PSQI), Epworth Sleepiness Scale(ESS), Self-rating Depression Scale(SDS), Self-rating Anxiety Scale(SAS) and Symptom Checklist 90(SCL-90) were for comparison. Results The scores of PSQI, ESS, SAS and SDS in OSAHS group were significantly higher than those in control group, and the scores of ESS, SDS and SAS in severe group were significantly higher than those in mild-moderate group(P<0.05). There were significant differences in total score of SCL-90 and its all factors except for obsessive state between OSAHS group and control group;and between severe group and mild-moderate group(P<0.05).Conclusion The subjective sleep quality, daytime excessive sleepiness, depression, anxiety and mental health of obese patients with OSAHS are all severer than those without OSAHS, and the degree is increased with the severity of OSAHS.

关 键 词：肥胖 阻塞性睡眠呼吸暂停低通气综合征 睡眠质量 抑郁 

分 类 号：Q428[生物学—神经生物学] R723.14[生物学—生理学]