MSCT多模态分析技术高原不同民族健康成年男性腹部脂肪分布的分析研究  

Analysis of abdominal adipose distribution in healthy adult males of different ethnic groups in the plateau area by multi-modal analysis of MSCT

作　　者：张轶凡[1,2,3] 白振忠 杨燕青[1] 格日力 ZHANG Yifan;BAI Zhenzhong;YANG Yanqing;GE Rili(Department of Nuclear Medicine,Qinghai Provincial People's Hospital,Xining,Qinghai 810001,China;Research Center for High Altitude Medicine;Qinghai - Utah Joint Research Key Lab for High Altitude Medicine)

机构地区：[1]青海省人民医院核医学科,青海西宁810001 [2]青海大学高原医学研究中心 [3]青海-犹他高原医学联合重点实验室

出　　处：《徐州医科大学学报》2019年第3期176-180,共5页Journal of Xuzhou Medical University

基　　金：国家自然科学基金(31571231)

摘　　要：目的利用多排螺旋CT(multi-slice spiral CT,MSCT)多模态分析技术(multi-modality work place,MMWP)探讨高原不同民族腹部脂肪分布的差异及影响因素。方法分别测量高原地区不同民族健康成年男性腹部皮下脂肪组织(subcutaneous adipose tissue,SAT)和内脏脂肪组织(visceral adipose tissue,VAT)体积。并分别对不同海拔高度进行差异性和相关性分析。结果藏、回两族与汉族对比腹部皮下脂肪体积(subcutaneous fat volume,SV)无差异(P>0.05),藏族腹部内脏脂肪体积(visceral fat volume,VV)和VV/(SV+VV)低于汉族(P=0.004、0.01)。回族与汉族对比VV和VV/(SV+VV)(%)无差异(P>0.05)。各民族高低海拔间比较,VV/(SV+VV)(%)高海拔组低于低海拔组(P=0.028.0.022、0.017)。汉、藏、回族VV/(SV+VV)(%)与海拔高度均存在不同程度负相关(P=0.024、0.049、0.005)。结论MMWP能够通过对腹部各部位脂肪体积精准测量而对腹部脂肪分布进行全面评估。藏族通过对高原环境长期的遗传适应,内脏脂肪占腹部总脂肪体积较小。并且腹部脂肪分布与低氧、寒冷环境有关。随着海拔升高,环境氧浓度和温度降低,内脏脂肪占腹部总脂肪体积减小。Objective To explore the differences and influencing factors of abdominal subcutaneous adipose tissue (SAT) distribution in different ethnic groups in the plateau area by multi-slice spiral CT (MSCT) multi-modal analysis technique.Methods MSCT multi-modality work place (MMWP) technique was used to measure SAT and visceral adipose tissue (VAT) in healthy adult males of different ethnic groups in the plateau area.The distribution of abdominal fat in these subjects at different altitudes was analyzed.Results There was no significant difference in subcutaneous fat volume (SV) between Tibetan and Hui ethnic groups and Han nationality (P>0.05), and visceral fat volume (VV) and VV/SV 4-VV in Tibetan ethnic group were lower than those in Han nationality (P=0.004 ,0.01).There was no significant difference in VV and VV/SV + VV (%) between Hui ethnic group and Han nationality (P>0.05).Compared with the high altitude groups, the VV/SV + VV (%) in high altitude groups was lower than that in low altitude groups (P=0.028 , 0.022, 0.017).There were negative correlations between VV/SV + VV (%) and altitude in Han, Tibet and Hui nationality (P=0.024, 0.049, 0.005).Conclusions MMWP technique can provide a comprehensive assessment of abdominal fat distribution by accurately measuring the volume of fat in various parts of the abdomen.Through long-term genetic adaptation to plateau environment, visceral fat in Tibetan population accounts for a small volume of total abdominal fat.The abdominal fat distribution is related to hypoxia and cold environment.With the increase of altitude, the oxy gen concentration in the atmosphere and temperature decrease, visceral fat accounted for the total abdominal fat volume decrease.

关 键 词：脂肪分布 民族 海拔高度 多排螺旋CT 

分 类 号：R445[医药卫生—影像医学与核医学]