ACS患者Hey、hs-CRP、SHG与GRACE评分的相关性研究  

The correlation of Hey, hs-CRP, SHG and GRACE scores in patients with ACS

作　　者：刘冰 曹鸿雁[2] 王金春 何鹏 LIU Bing;CAO Hong yan;WANG Jin chun;HE Peng(The FAW General Hospital The FourthHospital of Jilin University, 130011, China)

机构地区：[1]吉林省一汽总医院急诊科,长春130011 [2]吉林大学第一医院二部心内科

出　　处：《中国急救复苏与灾害医学杂志》2019年第3期205-207,共3页China Journal of Emergency Resuscitation and Disaster Medicine

摘　　要：目的研究急性冠状动脉综合征(acute coronary syndrome, ACS)患者同型半胱氨酸(homocysteine,Hey)、超敏C反应蛋白(high sensitivity C reactive protein,hs-CRP)、应激性咼血糖(stress hyperglycemia,SHG)与 GRACE评分的相关性。方法选择2012年1月-2018年1月在吉林省一汽总医院心内科行冠脉造影的患者150例,其中以冠脉造影正常的非冠心病组32例为对照组;ACS者118例,其中不稳定型心绞痛(unstable angina,UA)组37例,急性心肌梗死(acute myocardial infarction, AMI)组包括非ST段抬高型心肌梗死(non ST segment elevationmyocardial infarction,NSTEM1 )49例,ST段抬咼型心肌梗死(ST segment elevation myocardial infarction,STEMI)32例。上述3组患者入院后行常规实验室检查,采用全球急性冠状动脉事件注册评分(GRACE评分)计算分值并进行危险分层.分析Hcy、hs-CRP、SHG与GRACE评分及危险分层间的关系。结果血液中的Hcy、hs-CRP、SHG与GRACE评分及其危险分层间差异均有统计学意义(P<0.05),为ACS的独立影响因素。结论随着上述三项指标在体内含量的升高,GRACE评分增高,对ACS患者早期诊断、快速危险分层有重大临床意义。Objective Study the correlation between homocysteine (Hey),high sensitivity C reactive protein (hs-CRP), stress hyperglycemia (SHG) and and GRACE score in patients with acute coronary syndrome (ACS).Method Select 150 cases of coronary angiography in Department of Cardiology in our hospital from January 2012 to January 2018,32 cases of non coronary heart disease group with normal coronary angiography as control group, 118 cases of acute coronary syndrome (ACS),including 37 cases of unstable angina pectoris (UA) group,acute myocardial infarction (AMI) group included 49 cases of non ST segment elevation myocardial infarction (NSTEMI) and 32 cases of ST segment elevation myocardial infarction (STEMI).The 3 groups of patients underwent routine laboratory examination.The global acute coronary event registration score (GRACE score) was used to calculate the score and risk stratification,analyse the relationship between Hey hs-CRP SHG with GRACE score and risk stratification.Results The level of Hey hs-CRP SHG in blood were significantly different from GRACE score and risk stratification (P<0.05), which were independent factors of ACS. Conclusion With the increase of the three indexes in the body,the GRACE score increased,which was of great clinical significance for the early diagnosis and rapid risk stratification of ACS patients.

关 键 词：急性冠脉综合征 GRACE评分 同型半胱氨酸 超敏C反应蛋白 应激性高血糖 

分 类 号：R541.4[医药卫生—心血管疾病]