甲状腺癌超声造影及二维超声特征与颈部淋巴结转移的关系探讨  

Relationship between contrast-enhanced ultrasonography and two-dimensional ultrasound features of thyroid carcinoma and cervical lymph node metastasis

作　　者：刘利平[1] 崔荣荣 杨婧 刘静静[1] 李廷廷[1] 郝艳红[1] 刘晓芳[1] Liu Liping;Cui Rongrong;Yang Jing;Liu Jingjing;Li Tingting;Hao Yanhong;Liu Xiaofang(Department of Ultrasound,the First Affiliated Hospital of Shanxi Medical University,Taiyuan 030001,China;Department of Ultrasound,Shanxi Dayi Hospital,Taiyuan 030032,China;Department of Medical Administration,Emergency Center of Taiyuan City,Taiyuan 030007,China)

机构地区：[1]山西医科大学第一医院超声影像科,030001 [2]山西大医院超声科,030032 [3]山西省太原市急救中心医务科,030007

出　　处：《中华内分泌外科杂志》2019年第1期26-30,共5页Chinese Journal of Endocrine Surgery

基　　金：国家人社部留学回国人员科技活动择优资助项目(2016-366);山西省回国留学人员科研资助项目(2014-073).

摘　　要：目的探讨甲状腺癌常规超声特征、超声造影定量参数与颈部淋巴结转移之间的关系。方法选择2014年9月至2015年10月在山西医科大学第一医院超声科经手术病理证实的甲状腺癌患者89例共89个癌结节,分为有淋巴结转移组49例共49个癌结节与无淋巴结转移组40例共40个癌结节,以病理结果为金标准,分析其二维超声特征、超声造影增强模式及定量参数有无差异。结果①在淋巴结转移组与非转移组间,癌结节大小(T=-4.235)、是否与被膜接触(χ^2=12.269)、钙化类型(χ^2=8.901)、回声质地(χ^2=4.106)差异有统计学意义(P<0.05);②在淋巴结转移组与非转移组间峰值强度(T=2.035)差异有统计学意义(P<0.05)。结论甲状腺癌是否发生颈部淋巴结转移与癌结节大小、是否与被膜接触、伴微钙化、回声不均匀及超声造影峰值强度有关。Objective To explore the relationship between the features of thyroid carcinoma and its metastasis to cervical lymph nodes(MCLN)with conventional and contrast-enhanced ultrasound imaging.Methods Totally 89 thyroid carcinoma nodules were used in this study.The pathology of those samples was confirmed by surgical pathology at the First Affiliated Hospital of Shanxi Medical University from Sep 1,2014 to Oct 30,2015.The samples were divided into two groups based on the surgical pathology report:the group with MCLN(49)and the group without MCLN(40).Using the pathology report as gold standard,we analyzed the conventional ultrasound features,contrast-enhanced ultrasound enhancement pattern as well as the quantitative parameters.Results ① There was statistically significant difference in tumor size,contact of the tumor with capsule or not,microcalcification of the tumor,as well as echo texture of the thyroid carcinoma nodules between the groups(P<0.05).② There was statistically significant difference in peak intensity(PI)between the two groups(P<0.05).Conclusion There is a positive correlation between cervical lymph nodes metastasis and tumor size,with or without contact with fibrous capsule,with or without microcalcification,the internal echo as well as PI.

关 键 词：甲状腺癌 淋巴结转移 二维超声 超声造影 

分 类 号：R445.1[医药卫生—影像医学与核医学] R736.1[医药卫生—诊断学]