滋肾疏肝、活血祛瘀法干预滑胎患者血栓前状态的疗效观察  

Observation on Effect of Nourishing Kidney and Dredging Liver, Invigorating Blood and Removing Blood Stasis on Prethrombus Status of Patients with Slippery Fetus

作　　者：叶利群 杨脂 吴萍 钱诚 YE Liqun;YANG Zhi;WU Ping;QIAN Cheng(Gynecology Department, Ningbo Hospital of TCM , Ningbo 315000 ,Zhejiang, China)

机构地区：[1]宁波市中医院妇科,浙江宁波315000

出　　处：《中华中医药学刊》2019年第3期665-668,共4页Chinese Archives of Traditional Chinese Medicine

基　　金：浙江省中医药科技计划项目(2016ZB112);宁波市自然科学基金项目(2016A610201);宁波市中医学重点学科:中西医结合妇科学项目(2016-Z03)

摘　　要：目的:探讨滋肾疏肝、活血祛瘀法干预滑胎患者血栓前状态的临床效果。方法:滑胎患者100例根据数字表法随机分成观察组和对照组,每组50例,对照组采用低分子肝素组进行治疗,观察组采用滋肾活血安胎方进行治疗,比较分析两组的临床效果。结果:观察组的临床治疗总有效率与对照组相比无明显差异,不具有统计学意义(P>0.05)。两组患者在干预前凝血功能各项指标,血P值,症状积分和β-HCG值相比无明显差异,无统计学意义(P>0.05),通过不同方式进行治疗后,观察组除PT和BPC两项以外,其余凝血功能各项指标,β-HCG和症状积分均明显优于对照组,两组相比差异有统计学意义(P<0.05),但两组患者治疗后血P值无明显差异(P>0.05)。结论:滋肾疏肝,活血祛瘀法可以通过对以下方面的调节,提高胚胎存活率,如:调节纤溶功能,改变复发性流产血栓前状态,调节胎盘血液循环等多方面。滋肾活血安胎方因其疗效好、安全,提高胚胎存活率,所以有推广的价值。Objective: To explore the clinical effect of nourishing kidney and dredging liver and activating blood circulation and removing blood stasis on the prethrombosis of synovial patients. Method: 100 patients with habitual abortion according to the digital table method were randomly divided into observation group and control group, 50 cases in each group. The control group' s patients were treated with low molecular heparinand the observation group usedself - made Zishen Huoxue Antai Formula. We compared the clinical effect of two groups. Results : There was no significant difference in the total effective rate between the observation group and the control group ( P > 0. 05 ). Before intervention, blood coagulation function, blood P values, symptom integral and beta HCG value in two groups had no obvious difference ( P > 0. 05 ). After treatment by different ways, in the observation group, except PT and BPC, the rest of the blood coagulation function indicators, beta HCG and symptom score were significantly better than those of the control group ( P < 0. 05 ). But the two groups' blood P values after intervention had no obvious difference (P > 0. 05 ). Conclusion: The nourishing kidney and dredging liver and activating blood circulation and removing blood stasis method can improve the survival rate of embryonic through adjusting the fibrinolytic function, change of recurrent miscarriage before thrombus state, regulating placental blood circulation, etc. Because of its good effect and safety, it can improve the survival rate of embryo.

关 键 词：滋肾疏肝 活血祛瘀法 滑胎 血栓前状态 临床 效果 

分 类 号：R714.21[医药卫生—妇产科学]