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作 者:崇菲菲[1] 耿宝梁 朱鹏飞 赵开鹏 CHONG Fei-fei;GENG Bao-liang;ZHU Peng-fei(The Fourth Affiliated Hospital of Liaoning University of Traditional Chinese Medicine,Shenyang,110000,China)
机构地区:[1]辽宁中医药大学附属第四医院,沈阳110000
出 处:《中国初级卫生保健》2019年第3期58-60,共3页Chinese Primary Health Care
摘 要:目的探讨针灸联合身痛逐瘀汤加减治疗气滞血瘀型腰痛患者的疗效。方法选取2016年4月—2017年11月在辽宁中医药大学附属第四医院骨科治疗的气滞血瘀型腰痛患者100例,采用随机数表法分为对照组和观察组,每组各50例。14天为1个疗程,经过2个疗程治疗后进行疗效评估,观察治疗后两组患者的疗效、中医症状评分和生活质量改善情况;检测患者外周血中白介素1β(IL-1β)、肿瘤坏死因子α(TNF-α)水平,比较两组检测结果的差异及与病情、疗效的关系。结果观察组的治疗总有效率为88.0%,显著高于对照组的66.0%(P<0.05);治疗后,观察组与对照组比较中医症状评分显著降低,差异有统计学意义(P<0.05);两组患者治疗后生活质量评分均明显升高(P<0.05),观察组生活质量评分明显高于对照组,且差异显著(P<0.05);两组患者治疗后血清IL-1β、TNF-α较治疗前均明显降低,且观察组较对照组变化更明显(P<0.05)。结论运用针灸联合身痛逐瘀汤加减治疗临床中确诊的气滞血瘀型腰痛患者疗效显著,与单纯中药方剂治疗比较优势明显;临床上可以通过IL-1β、TNF-α联合检测值的异常变化预测气滞血瘀型腰痛患者的病情严重程度和治疗效果。OBJECTIVE To explore the efficacy of acupuncture combined with traditional Chinese medicine( TCM) in the treatment of patients with low back pain with qi stagnation and blood stasis. METHODS 100 patients with qi stagnation and blood stasis type low back pain treated in Orthopedics Department from April 2016 to November 2017 were randomly divided into control group and observation group( 50 cases in each group). 14 days was a treatment course. After 2 courses of treatment, the curative effect was evaluated. The curative effect, TCM symptom score and quality of life improvement of the two groups were observed. The interleukin-1(3(IL-1 β) and tumor necrosis fatora(TNF-α) in peripheral blood were detected. The relationship between the disease and the effect were compared. RESULTS The total effective rate of the observation group was 88.0%, which was significantly higher than the control group(66.0%, P<0.05). After treatment, the TCM symptom scores of the observation group and the control group were significantly lower(P< 0.05). The quality of life scores of the two groups were significantly increased after treatment(P<0.05). The quality of life scores of the observation group were significantly higher than the control group, and the difference was significant(P<0.05). The serum IL-1β and TNF were treated after treatment, and the observation group was more obvious(P<0.05). CONCLUSION Acupuncture combined with body pain and phlegm decoction in the treatment of patients with qi stagnation and blood stasis type of low back pain had significant effect compared with the TCM prescription treatment. Abnormal changes in the combined detection of IL-1β and TNF-α could predict the severity and treatment of patients with qi stagnation and blood stasis type of low back pain.
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