芫苓消水散联合IL-2腹腔灌注治疗癌性腹水60例  

Yuan Ling Xiao Shui Powder and Intraperitoneal Perfusion of IL-2 in Treating 60 Cases of Malignant Ascites

作　　者：李雪妮 姜春状 刘艳霞 LI Xueni;JIANG Chunzhuang;LIU Yanxia(Department of Oncology,Weihai Municipality TCM Hospital,Weihai 264200,China)

机构地区：[1]威海市中医院肿瘤科,山东威海264200

出　　处：《西部中医药》2019年第2期110-112,共3页Western Journal of Traditional Chinese Medicine

摘　　要：目的:观察芫苓消水散联合IL-2腹腔灌注治疗癌性腹水的临床疗效。方法:将120例癌性腹水患者随机分为对照组和观察组各60例,对照组采用IL-2腹腔灌注治疗,观察组采用IL-2腹腔灌注联合芫苓消水散膏药外敷治疗,治疗2周后比较2组临床疗效、中医证候评分、腹围、腹水深度、24小时尿量、生活质量和毒副反应发生情况。结果:总有效率观察组为85.0%,对照组为65.0%,2组比较差异有统计学意义(P<0.05)。腹围、腹水深度、24小时尿量、KPS评分、中医证候评分治疗前后2组组内比较,差异有统计学意义(P<0.05);治疗后2组组间比较差异也有统计学意义(P<0.05)。观察组除贫血、恶心呕吐外,其余毒副反应发生率均低于对照组,差异有统计学意义(P<0.05)。结论:采用芫苓消水散联合IL-2腹腔灌注治疗癌性腹水患者,效果满意,毒副反应少。Objective:To observe clinical effects of YuanLing XiaoShui powder and intraperitoneal perfusion of IL-2 in treating malignant ascites.Methods:All 120 patients were randomized into the control group and the observation group,60 cases each group,the control group adopted intraperitoneal perfusion of IL-2,the observation group used intraperitoneal perfusion of IL-2 and YuanLing XiaoShui powder for external application,after treating two weeks,to compare curative effects,TCM syndrome scores,abdominal perimeter,the depth of ascites,24hour urinary volume,quality of life,toxic reactions between both groups.Results:Total effective rate of the control group was 65.0%,lower than 85.0%of the observation group,and the difference showed statistical meaning(P<0.05).The difference had statistical meaning in the comparisons of abdominal perimeter,the depth of ascites,24hour urinary volume,KPS scores and TCM syndrome scores within two groups before and after treating(P<0.05);the difference was statistically significant in the comparisons between both groups after treating(P<0.05).The observation group was lower than the control group in the incidences of toxic reactions except anemia,sick and vomiting(P<0.05).Conclusion:YuanLing XiaoShui powder and intraperitoneal perfusion of IL-2 in treating malignant ascites could obtain satisfactory effects with minor toxic reactions.

关 键 词：癌性腹水 芫苓消水散 IL-2 腹腔灌注 

分 类 号：R442.5[医药卫生—诊断学]