趋化因子RANTES在颅脑损伤的研究进展  

Research progress of chemokine RANTES in craniocerebral injury

作　　者：刘娜娜 冀兵[2] Liu Nana;Ji Bing(First School of Clinical Medicine, Shanxi Medical Univercity, Taiyuan 030001, China;Department of Emergency, The First Hospital of Shanxi Medical Univercity, Taiyuan 030001, China)

机构地区：[1]山西医科大学第一临床医学院,太原030001 [2]山西医科大学第一医院急诊科,太原030001

出　　处：《中华神经创伤外科电子杂志》2019年第2期117-119,共3页Chinese Journal Of Neurotraumatic Surgery：Electronic Edition

基　　金：国家临床重点专科建设项目(2013-544)

摘　　要：调节激活正常T细胞表达和分泌细胞因子(RANTES)是一类CC家族趋化因子,对多种细胞有趋化作用,参与炎症反应,调节细胞的生长和分化,并参与中枢神经系统疾病的病理、生理过程。作为一种典型的趋化因子,RANTES在颅脑损伤时发挥重要意义。本文主要讨论趋化因子RANTES和颅脑损伤的关系及在颅脑损伤发挥的作用,指导临床检测和治疗。Regulated upon activation normal T expressed and secreted (RANTES) is a class of C-C family chemokines that have chemotactic effects on various cells, participate in inflammatory responses, and regulate the growth and differentiation of cells. In addition, it is also involved in the pathological and physiological processes of central nervous system diseases. As a typical chemokine, RANTES plays an important role in craniocerebral injury. Therefore, this paper mainly discusses the relationship between chemokine RANTES and brain injury and its role in craniocerebral injury, so as to guide clinical detection and treatment.

关 键 词：调节激活正常T细胞表达和分泌细胞因子 颅脑损伤 研究进展 

分 类 号：R651.15[医药卫生—外科学]