合并右心衰竭对慢性阻塞性肺疾病急性加重频率及严重程度的影响  

Influence of right heart failure on the frequency and severity of acute exacerbations of chronic obstructive pulmonary disease

作　　者：林祥兵 丁震[1] LIN Xiang-bi ng;DING Zhen(Hefei First Peoples Hospital,Hefei 230061,China)

机构地区：[1]合肥市第一人民医院,合肥230061

出　　处：《内科急危重症杂志》2019年第1期45-47,共3页Journal of Critical Care In Internal Medicine

摘　　要：目的:探讨合并右心衰竭对慢性阻塞性肺疾病(COPD)急性加重频率以及严重程度的影响。方法:选择COPD患者274例,其中无右心衰竭患者194例,合并右心衰竭患者80例,随访1年,记录其急性加重事件发生情况。结果:合并右心衰竭组急性加重次数明显高于无右心衰竭组[(1.33±0.49)次/年vs(0.86±0.25)次/年,P<0.05]。合并右心衰竭组急性加重严重程度(血气分析、呼吸困难评分、不良事件和严重不良事件)显著高于无右心衰竭组(均P<0.05)。结论 :合并右心衰竭可能是COPD发生多次和严重急性加重的重要危险因素。Objective:To explore the effect of comorbid right heart failure on the frequency and the severity of acute exacerbations of chronic obstructive pulmonary disease(AECOPD).Methods:274 cases of COPD were enrolled in this study,including 194 patients without heart failure and 80 patients with right heart failure.All cases were followed up for 1 year and their acute exacerbations were recorded.Results:The frequency of acute exacerbations in the combined right heart failure group(1.33±0.49)was significantly higher than that in the non-right heart failure group(0.86±0.25,P<0.05).The severity of acute exacerbations in the combined right heart failure group was also significantly greater than that in the non-right heart failure group(such as blood gas analysis,dyspnea score,adverse events and severe adverse events,P<0.05).Conclusion:Right heart failure may be an risk factor for multiple and severe AECOPD.

关 键 词：慢性阻塞性肺疾病 急性加重 右心衰竭 

分 类 号：R541.61[医药卫生—心血管疾病] R563[医药卫生—内科学]