莲必治注射液联合头孢曲松钠他唑巴坦钠治疗老年肺炎的临床效果  

Clinical effect of Lianbizhi Injection combined with Ceftriaxone Sodium and Tazobactam Sodium in the treatment of senile pneumonia

作　　者：郭玉梅[1] 庚俐莉[1] 舒姣洁 张芸[1] 徐显楠 臧士国 刘昊 GUO Yu-mei;GENG Li-li;SHU Jiao-jie;ZHANG Yun;XU Xian-nan;ZANG Shi-guo;LIU Hao(Department of Emergency ICU, Central Hospital of Dalian City, Liaoning Province, Dalian 116033, China)

机构地区：[1]大连市中心医院急诊ICU,辽宁大连116033

出　　处：《中国当代医药》2019年第9期41-43,共3页China Modern Medicine

基　　金：国家自然科技计划项目(81301721

摘　　要：目的探讨莲必治注射液联合头孢曲松钠他唑巴坦钠治疗老年肺炎的临床效果。方法选取我院2017年6月～2018年6月收治的90例肺炎老年患者作为研究对象,按照随机数字表法将其分为对照组(45例)和联合组(45例)。对照组患者采用头孢曲松钠他唑巴坦钠治疗,联合组患者采用莲必治注射液联合头孢曲松钠他唑巴坦钠治疗,治疗2周后,比较两组患者的症状改善情况、用药效果及治疗前后炎症指标改善情况。结果联合组患者的退热时间、咳嗽消失时间及憋喘时间均短于对照组,差异有统计学意义(P<0.05)。联合组患者的用药总有效率高于对照组,差异有统计学意义(P<0.05)。两组患者治疗后的C-反应蛋白(CRP)、肿瘤坏死因子-α(TNF-α)及白细胞介素6(IL-6)水平均低于治疗前,且联合组低于对照组,差异有统计学意义(P<0.05)。结论在头孢曲松钠他唑巴坦钠用药基础上联合莲必治注射液治疗能够显著改善老年肺炎患者的临床症状及炎症指标,具有良好的应用效果。Objective To investigate the clinica effect of Lianbizhi Injection combined with Ceftriaxone Sodium and Tazobactam Sodium in the treatment of senile pneumonia. Methods A total of 90 elderly patients with pneumonia admitted to our hospital from June 2017 to June 2018 were selected as the study subjects. According to the random number table method, they were divided into the control group (45 cases) and the combined group (45 cases). The control group was treated with Ceftriaxone Sodium and Tazobactam Sodium, the combined group was treated with Lianbizhi Injection and Ceftriaxone Sodium and Tazobactam Sodium. After 2 weeks of treatment, the improvement of symptoms, medication effect and inflammation indicators before and after treatment were compared between the two groups. Results The antipyretic time, cough disappearance time and wheezing time in the combined group were shorter than those in the control group, and the differences were statistically significant (P<0.05). The total effective rate of the combined group was higher than that of the control group , and the difference was statistically significant (P<0.05). After treatment, the levels of C-reactive protein (CRP), tumor necrosis factor-α(TNF-α) and interleukin-6 (IL-6) in the two groups were lower than those before treatment, and the levels of CRP, TNF-α and IL-6 in the combined group were lower than those in the control group, and the differences were statistically significant (P<0.05). Conclusion On the basis of Ceftriaxone Sodium and Tazobactam Sodium combined with Lianbizhi Injection can significantly improve the clinical symptoms and inflammatory indicators of senile pneumonia patients, with good application effect.

关 键 词：老年人 肺炎 莲必治注射液 头孢曲松钠他唑巴坦钠 炎症指标 

分 类 号：R563.1[医药卫生—呼吸系统]