糖尿病患者和非糖尿病健康体检者眼表病变的临床分析  

An clinical analysis of treating ocular surface lesions in diabetics and non-diabetic healthy checkups

作　　者：廖志群 Liao Zhiqun

机构地区：[1]广州市海珠区中医医院,广东广州510220

出　　处：《中医临床研究》2019年第7期51-52,共2页Clinical Journal Of Chinese Medicine

摘　　要：目的:分析糖尿病患者和非糖尿病健康体检者眼表病变带来的影响。方法:研究对象选取2016年12月-2018年1月笔者参与会诊的250例糖尿病患者作为观察组和具有可比性的50例非糖尿病健康体检者作为对照组,回顾分析两组参与者的BUT检查、泪液分泌试验、角膜荧光素染色和结膜印迹细胞法等检查结果,比较两组参与者空腹血糖、餐后2 h血糖、糖化血红蛋白及血脂的数值。结果:观察组BUT检查和泪液分泌试验检查的结果均明显低于对照组(P <0.05);对照组角膜荧光素染色结果正常,而观察组在角膜或结膜处有黄绿色荧光素;观察组的空腹血糖、餐后2 h血糖、糖化血红蛋白及血脂均明显高于对照组(P <0.05)。结论:糖尿病患者会引发严重的眼表方面的病变,要做好预防监察工作,减少患者致盲概率。Objective:To analyze the effects of ocular surface lesions in diabetic patients and non-diabetic healthy checkups.Methods:250 patients with diabetes mellitus who participated in the consultation were selected as the observation group and 50 comparable healthy non-diabetic people were selected as the control group.Retrospective analysis of BUT examination,tear secretion test,corneal fluorescein staining,and conjunctival imprinting cell test results were performed in both groups.The fasting blood glucose,postprandial2 hours blood glucose,glycated hemoglobin,and blood lipids were compared between two groups.Results:The results of BUT examination and tear secretion test in the observation group were significantly lower than those in the control group(P<0.05).The corneal fluorescein staining results were normal in the control group,while yellow-green fluorescein was observed in the cornea or conjunctiva in the observation group.The fasting blood glucose,postprandial blood glucose,glycosylated hemoglobin,and blood lipids in the observation group were significantly higher than those in the control group(P<0.05).Conclusion:Diabetics mellitus can cause severe ocular surface lesions,and prevention monitoring should be done to reduce the probability of blindness.

关 键 词：糖尿病 眼表病变 泪液分泌试验 角膜荧光素染色 临床分析 

分 类 号：R587.1[医药卫生—内分泌]