微创穿刺碎吸术联合活血利水法治疗高血压脑出血的临床研究  

Clinical Study on Treatment of Hypertensive Cerebral Hemorrhage with Minimally Invasive Puncture and Aspiration Operation Combined with Promoting Blood Circulation and Diuresis Method

作　　者：王付启 赵平丽 王媛 WANG Fuqi;ZHAO Pingli;WANG Yuan(Department of Emergency,Zhumadian Hospital of Traditional ChineseMedicine,Zhumadian 463000,China)

机构地区：[1]驻马店市中医院急诊科,河南驻马店463000

出　　处：《中西医结合研究》2019年第2期61-64,共4页Research of Integrated Traditional Chinese and Western Medicine

基　　金：河南省中医药科学研究专项课题(No.2016ZY2053)

摘　　要：目的观察微创穿刺碎吸术联合活血利水法治疗高血压脑出血患者的临床疗效。方法选取2014年7月—2016年7月本院收治的高血压脑出血患者60例,按照随机数字表法分为观察组和对照组,每组30例。对照组患者予以微创穿刺碎吸术治疗,观察组患者在对照组治疗基础上予以活血利水法治疗。连续治疗14 d后,比较2组患者治疗前后血清CRP、TNF-α、IL-1β、IL-6的水平变化;比较2组患者治疗前后NIHSS及Barthel评分、血肿量变化;比较2组患者临床疗效。结果治疗后,2组患者血清CRP、TNF-α、IL-1β、IL-6水平均较治疗前明显下降,且观察组显著低于对照组(P<0.05);2组患者NIHSS评分、血肿量均较治疗前明显下降,Barthel评分均较治疗前明显升高,且观察组改善程度显著优于对照组(P<0.05);观察组患者临床治疗总有效率为96.67%,显著高于对照组的86.67%(P<0.05)。结论应用微创穿刺碎吸术联合活血利水法治疗高血压脑出血患者临床疗效显著,可显著下调血清CRP、TNF-α、IL-1β、IL-6水平,减少颅内血肿量,改善神经功能,促进个人生活能力恢复,值得推广应用。Objective To observe the clinical effect of minimally invasive puncture and aspiration operation combined with promoting blood circulation and diuresis method for hypertensive cerebral hemorrhage. Methods From July 2014 to July 2016,sixty patients with hypertensive cerebral hemorrhage were selected and randomly divided into observation group and control group according to random digital table method,with 30 cases in each group.The patients in the control group were treated with minimally invasive puncture and aspiration operation,and the patients in the observation group were treated with promoting blood circulation and diuresis method on the basis of the control group.After 14 days of continuous treatment,the changes of serum CRP,TNF-α,IL-1 β,IL-6 levels before and after treatment were compared between the two groups.The scores of NIHSS and Barthel and the volume of hematoma between the two groups were compared before and after treatment,and the total effective rates of clinical treatment between the two groups were compared. Results After treatment,the serum levels of CRP,TNF-α, IL-1β and IL-6 in the two groups were significantly lower than those before treatment,and the observation group was significantly lower than that of the control group( P <0.05).The NIHSS scores and the volume of hematoma of the two groups were significantly lower than those before treatment,the Barthel scores were significantly higher than those before treatment,and the improvement degree of the observation group was significantly better than that of the control group( P <0.05).The total effective rate of the observation group was 96.67%,which was significantly higher than that of the control group(86.67%)( P <0.05 ). Conclusion The treatment of hypertensive cerebral hemorrhage with minimally invasive puncture and aspiration operation combined with promoting blood circulation and diuresis method has a significant clinical effect.It can obviously decrease the levels of serum CRP,TNF-α,IL-1β,IL-6,reduce the amount of intracranial he

关 键 词：微创穿刺碎吸术 活血利水法 高血压脑出血 

分 类 号：R651.12[医药卫生—外科学]