某汽车制造企业长期低浓度混苯接触对男性外周血的影响  

Effect of long-term low-concentration mixed benzene exposure on male peripheral blood in an automobile manufacturing enterprise

作　　者：李燕茹 谢春姣 丘丛玺 林秋月 刘移民 Li Yanru;Xie Chunjiao;Qiu Congxi;Lin Qiuyue;Liu Yimin(Guangzhou Occupational Disease Prevention and Treatment Hospital,Guangzhou 510620,China)

机构地区：[1]广州市职业病防治院,广州医科大学职业与环境卫生研究所,510620

出　　处：《中华劳动卫生职业病杂志》2019年第2期119-121,共3页Chinese Journal of Industrial Hygiene and Occupational Diseases

基　　金：广州市医学重点学科建设项目(穗卫科教【2016】27号);广东省"十二五"医学重点专科(粤卫函【2012】20号);广州市"121人才梯队工程"后备人才项目(穗人社发【2011】167号).

摘　　要：目的探讨长期低浓度混苯接触对男性工人外周血的影响。方法采用横断面调查方法,选取某汽车制造企业2012年1月~2016年12月连续5年均进行职业健康检查的452名接触混苯(苯、甲苯、二甲苯)男性工人作为接触组,选取同期进行职业体检的438名男性行政后勤管理人员作为对照组,比较两组人员的外周血检测结果,同时对作业场所职业病危害因素进行检测,以分析其相关关系。结果2012~2016年,该汽车企业车间有低剂量的混苯暴露,但检测结果均符合职业接触限值要求。与对照组比较,接触组红细胞(WBC)、中性粒细胞(NENT)、红细胞(RBC)、血红蛋白(Hb)的均值差异均有统计学意义(P<0.05),血小板均值差异无统计学意义(P>0.05);与对照组比较,接触组外周血主要指标异常率低,NEUT、RBC、Hb指标差异有统计学意义(P<0.05),WBC、PLT差异无统计学意义(P>0.05)。结论尚不能认为长期低浓度混苯接触可引起男性外周血指标的改变。Objective To investigated the effect of long-term low-concentration mixed benzene exposure on peripheral blood of male workers.Methods A case-control study was conducted to select 452 male workers exposed to mixed benzene(benzene,toluene,xylene)for five consecutive years from January 2012 to December 2016 in an automobile manufacturer as case group,and 438 male administrative and logistic managers who underwent physical examination during the same period as control group.The peripheral blood of the two groups was tested and compared,and the occupational hazards in the workplace were detected.Results There were low dose exposure to mixed benzene in the enterprise,but the test results met the occupational exposure limit requirements.During the five years from 2010 to 2016,between the two groups of workers,the mean values of WBC,NEUT,RBC and Hb were statistically different(P<0.05).There was no statistical difference(P>0.05)in the mean value of PLT.The abnormal rate of main peripheral blood indexes in the control group was higher than that in the exposed group.There were significant differences in NEUT,RBC and Hb(P<0.05),but no significant differences in WBC and PLT(P>0.05).Conclusion It can not be concluded that long-term low-concentration mixed benzene exposure can cause the change of peripheral blood index.

关 键 词：苯 血液系统 男性 低浓度 

分 类 号：R135[医药卫生—劳动卫生]