泰顺畲族人群血脂异常患病率及畲族人群低密度脂蛋白胆固醇与颈动脉斑块的关系  

Prevalence of dyslipidemia in the She population in Taishun county and the relationship between low density lipoprotein cholesterol and carotid plaque in the She population

作　　者：龚志广[1] 杨晓国 郑炎焱 包雅崇 雷德旺 黄海斌[4] GONG Zhi-guang;YANG Xiao-guo;ZHENG Yan-yan;BAO Ya-chong;LEI De-wang;HUANG Hai-bin(Neurology Department,the People's Hospital of Taishun County,Wenzhou 325500;Neurology Department,the People's Hospital of Wenzhou,Wenzhou 325000;Internal Medicine Department,Siqian She Nationality Town Health Center in Taishun County,Wenzhou 325501;Laboratory Department,the People's Hospital of Taishun County,Wenzhou 325500,China)

机构地区：[1]泰顺县人民医院神经内科,浙江温州325500 [2]温州市人民医院神经内科,浙江温州325000 [3]泰顺县司前畲族镇卫生院内科,浙江温州325501 [4]泰顺县人民医院检验科,浙江温州325500

出　　处：《临床医学研究与实践》2019年第9期8-9,12,共3页Clinical Research and Practice

基　　金：泰顺县科技计划项目[泰科〔2017〕14号-4]

摘　　要：目的探讨泰顺县畲族人群血脂异常患病率及畲族人群低密度脂蛋白胆固醇(LDL-C)与颈动脉斑块的关系。方法随机选取2016年8月至2018年8月我院收治的泰顺畲族人群80例为研究对象,将存在颈动脉斑块的40例受检者纳入存在组,将不存在颈动脉斑块的40例受检者纳入未存在组。比较两组受检者的临床资料、小颗粒致密LDL-C(sdLDL-C)水平及血脂异常情况。结果存在组受检者的年龄、合并高血压、糖尿病的比例、TC、TG水平均显著高于不存在组,差异具有统计学意义(P<0.05);存在组受检者的sdLDL-C水平显著高于不存在组,差异具有统计学意义(P<0.05);存在组受检者的血脂异常患病率显著高于不存在组,差异具有统计学意义(P<0.05);sdLDL-C水平和颈动脉斑块形成呈显著正相关(r=0.4017,P<0.05)。结论泰顺畲族人群血脂异常患病率高,畲族人群sdLDL-C水平与颈动脉斑块呈显著正相关,值得临床充分重视。Objective To investigate the prevalence of dyslipidemia in the She population in Taishun county and the relationship between low density lipoprotein cholesterol(LDL-C)and carotid plaque in the She population.Methods A total of 80 cases of She population in Taishun county treated in our hospital from August 2016 to August 2018 were randomly selected as the study objects.A total of 40 objects with carotid plaque were included in existing group,40 objects with no carotid plaque were included in non-existing group.The clinical data,the levels of small particle dense LDL-C(sdLDL-C)and dyslipidemia of the two groups were compared.Results The age,proportions of hypertension and diabetes,the levels of TC and TG of objects in the existing group were significantly higher than those in the non-existing group,and the differences were statistically significant(P<0.05).The level of sdLDL-C in the existing group was significantly higher than that in the non-existing group,and the difference was statistically significant(P<0.05);the prevalence of dyslipidemia in the existing group was significantly higher than that in the non-existing group,and the difference was statistically significant(P<0.05).There was a significant positive correlation between the level of sdLDL-C and carotid plaque formation(r=0.4017,P<0.05).Conclusion The prevalence of dyslipidemia in the She population in Taishun county is high,and there is a significant positive correlation between the level of sdLDL-C and carotid plaque in the She population,which is worthy of the clinical full attention.

关 键 词：泰顺畲族人群 血脂异常 低密度脂蛋白胆固醇 颈动脉斑块 

分 类 号：R589.2[医药卫生—内分泌]