无偿献血者血液报废情况分析  

Analysis of blood discard in voluntary blood donation during 2013 to 2017 in Zhengzhou, China

作　　者：刘蕾[1] 王莉[1] 刘玉振[1] LIU Lei;WANG Li;LIU Yuzhen(Henan Red Cross Blood Center,Zhengzhou 450012,China)

机构地区：[1]河南省红十字血液中心,河南郑州450012

出　　处：《中国输血杂志》2019年第1期49-52,共4页Chinese Journal of Blood Transfusion

摘　　要：目的了解郑州市无偿献血者血液报废情况,以便制定相应对策,减少血液报废。方法采用唐山启奥软件系统对郑州市2013—2017年无偿献血者血液检验报废率和非检验报废率做统计分析。结果郑州市2013—2017年无偿献血者血液检验报废率2.496%(24 402/977 761),各项报废率从高到低依次为:ALT 1.406%(13 751/977 761)、HBsAg 0.362%(3 541/977 761)、抗-HCV 0.321%(3 136/977 761)、抗-TP 0.269%(2 633/977 761)、抗-HIV 0.137%(1 341/977 761);除2013和2014年报废率无显著差异外(P>0.05),各年度之间报废率比较有显差异(P<0.05),其中2014年报废率最高2.993%(5 726/191 315),2017年报废率最低2.001%(4 285/214 115),平均报废率(2.521±0.428)%。核酸检测报废率为0.488‰(371/760 687),各项报废率从高到低依次为:HBV DNA 0.480‰(365/760 687),HIV RNA 0.005‰(4/760 687),HCV RNA 0.003‰(2/760 687);HBV DNA报废率明显高于HCV RNA及HIV RNA(P<0.01),HCV RNA和HIV RNA报废率无明显差异(P>0.05)。非检验总报废率为3.206%(134 335/4 189 536),按报废原因从高到低依次为:脂血2.797%(117 182/4 189 536)、血袋破损0.235%(9 848/4 189 536)、血凝块0.086%(3 604/4 189 536)、过期0.062%(2 597/4 189 536)、血液不足量0.023%(945/4 189 536)、溶血0.003%(116/4 189 536)、色泽异常0.001%(43/4 189 536);按血液制剂品种报废率:浓缩血小板42.63%(3 832/8 988)、冰冻血浆12.403%(117 648/948 521)、病毒灭活冰冻血浆1.361%(8 243/605 521)、冷沉淀0.431%(1 209/280 368)、全血0.393%(17/4 331)。结论加强对献血者献血前的咨询,规范采供血以及临床用血等各环节的操作,有助于减少血液报废。Objective To analyze the status of blood discard from voluntary blood donation in Zhengzhou in the period ranging from 2013 to 2017,so as to propose countermeasures to minimize the blood wasted. Methods The rate of blood donations discarded due to detection and non-detection causes of the targeted years were statistically analyzed by Tangshan Oi' ao software system. Results Within the studied period,the total rate of blood discard was 2. 496%( 24 402 /977 761). The most common cause of blood discard owing to blood screening was ALT,accounting for 1. 406%( 13 751 /977 761),followed by HBsAg 0. 362%( 3 541 /977 761),anti-HCV 0. 321%( 3 136 /977 761),anti-TP 0. 269%( 2 633 /977 761), and anti-HIV 0. 137%( 1 341 /977 761). Regarding annual discard rate,a significant difference between each year was observed except for 2013 and 2014. The mean annual discard rate was ( 2. 521±0. 428)%,ranging from 2. 001%( 4 285 /214 115) in 2017 to 2. 993%( 5 726 /191 315) in 2014. The total rate of blood discarded owing to nucleic acid detection was 0. 488‰( 371 /760 687),among which HBV DNA accounted for 0. 480‰( 365 /760 687),HIV RNA 0. 005‰( 4 /760 687),and HCV RNA 0. 003‰( 2 /760 687). Comparing NAT discard rate,HBV DNA discard rate was significantly higher than that of HCV RNA and HIV RNA,and there was no significant difference between HCV RNA and HIV RNA discard rate ( P>0. 05). The total non-detection discard rate was 3. 206%( 134 335 /4 189 536),among which lipemia ranking in the first with a rate of 2. 797%( 117 182 /4 189 536),followed by bag leakage 0. 235%( 9 848 /4 189 536),blood clot 0. 086%( 3 604 /4 189 536),expired blood 0. 062%( 2 597 /4 189 536),blood deficiency 0. 023%( 945 /4 189 536),hemolysis 0. 003%( 116 /4 189 536) and abnormal color 0. 001%( 43 /4 189 536). In addition,discard rates in blood preparations were as follows : 42. 63% in concentrated platelets ( 3 832 /8988),12. 4033% in frozen plasma ( 117 648 /948 521),1. 361% in inactivated frozen plasma ( 8 243 /605 521),0. 431% in cryoprecipitation

关 键 词：血液报废 血液检验 核酸检测 血液制备 献血者咨询 采供血 临床用血 

分 类 号：R457.1[医药卫生—治疗学] R193.3[医药卫生—临床医学]