利托君联合烯丙雌醇治疗复发性流产的效果观察  

Effects of Ritodrine combined with Allylestrenol on recurrent abortion

作　　者：赵红果[1] ZHAO Hongguo(Women & Infants Hospital of Zhengzhou, Zhengzhou 450000 Henan, China)

机构地区：[1]郑州市妇幼保健院,河南郑州450000

出　　处：《中国民康医学》2019年第5期14-15,24,共3页Medical Journal of Chinese People’s Health

摘　　要：目的:观察利托君联合烯丙雌醇治疗复发性流产的效果。方法:选取78例复发性流产患者为研究对象。采用随机数字表法将其分为对照组与观察组各39例。对照组给予烯丙雌醇联合硫酸镁治疗,观察组给予烯丙雌醇与利托君联合治疗。比较两组保胎成功率、不良反应发生率及血清β-人绒毛膜促性腺激素(β-HCG)、孕酮水平。结果:观察组保胎成功率为94.87%(37/39),明显高于对照组的69.23%(27/39),差异有统计学意义(P<0.05);观察组治疗后的孕酮、β-HCG水平明显优于对照组,差异有统计学意义(P<0.05);两组不良反应发生率比较,差异无统计学意义(P>0.05)。结论:利托君联合烯丙雌醇治疗复发性流产,可提高β-HCG和孕酮水平,提高孕妇的保胎成功率,且安全性高。Objective: To explore effects of Allylestrenol combined with Ritodrine in the treatment of recurrent abortion. Methods: 78 patients with recurrent abortion admitted to Zhengzhou women & infants hospital of Zhengzhou from May 2016 to May 2018 were selected as the objects. These patients were divided into control group and observation group according to the random number table method, 39 cases in each. The control group was treated with Allylestrenol and Magnesium sulfate, while the observation group was given Allylestrenol combined with Ritodrine.The success rate of fetus protection, adverse reaction rate, serum β-human chorionic gonadotrophin(β-HCG) and progesterone level were compared between the two groups. Results: The success rate of fetus protection in the observation group was 94.87%(37/39), which was significantly higher than that in the control group 69.23%(27/39), and the difference was statistically significant(P<0.05). After the treatment, the progesterone andβ-HCG levels in the observation group were significantly better than those of the control group, and the differences were statistically significant(P<0.05). There was no significant difference in the incidence of adverse reactions between the two groups(P>0.05). Conclusions: Ritodrine combined with Allylestrenol l in the treatment of recurrent abortion can increase the level of β-HCG and progesterone and improve the success rate of fetus protection in the pregnant women with high safety.

关 键 词：复发性流产 烯丙雌醇 利托君 硫酸镁 

分 类 号：R714.2[医药卫生—妇产科学]