CD8^+ T细胞与支气管哮喘关系研究进展  

Research progress of association between CD8^+ T lymphocytes and bronchial asthma

作　　者：徐敏[1] 王伟[2] XU Min;WANG Wei(Nursing School of Wuhan Railway Vocational College of Technology,Wuhan 430205,China)

机构地区：[1]武汉铁路职业技术学院医护学院,武汉430205 [2]武汉大学中南医院呼吸与危重症医学科,武汉430071

出　　处：《中国免疫学杂志》2019年第7期877-880,887,共5页Chinese Journal of Immunology

基　　金：国家自然科学基金(81670021)资助

摘　　要：CD8^+T细胞是一类异质的具有多种功能的T淋巴细胞亚群,在机体清除病原体感染、抗肿瘤以及介导器官移植排斥反应过程中发挥重要的调节作用。近年来,人们发现,CD8^+T细胞在哮喘的发病中也扮演重要角色。本文将对CD8^+T细胞的分类、功能以及其与哮喘之间的关系进行综述。CD8^+T cells are a group of heterogeneous T lymphocyte subsets with multiple functions.It plays an important role in the elimination of pathogen infection,anti-tumor and mediated rejection of organ transplantation.In recent years,it has been found that CD8^+T cells also play an important role in the pathogenesis of asthma.In this article,we reviewed the classification,function of CD8^+T lymphocytes and the relationship between CD8^+T cells and bronchial asthma.

关 键 词：CD8^+T细胞 CD4^+T细胞 支气管哮喘 

分 类 号：R562.2[医药卫生—呼吸系统]