中药药效物质的研究方法  

Research methods of pharmacodynamic substance of traditional Chinese medicine

作　　者：张延妮[1] 李娜[1] 景雁楠 ZHANG Yanni;LI Na;JING Yannan(The Key Laboratory of Medicinal Resources and Natural Pharmaceutical Chemistry,the Ministry of Education,School of Life Sciences,Shaanxi Normal University,Xi'an 710119,China)

机构地区：[1]陕西师范大学生命科学研究院药用资源与天然药物化学教育部重点实验室,西安710119

出　　处：《生命的化学》2019年第1期165-170,共6页Chemistry of Life

基　　金：中央高校基本科研业务费(GK201703078;GK201806001);陕西省重点研发计划项目(2018SF-287)

摘　　要：中药药效物质的研究是中药现代化研究的核心,科学阐明中药临床治疗的物质基础,是中药药效学研究的最终目标。现阶段中药药效物质基础研究方法主要有化学分离分析、生物色谱法和虚拟筛选等方法。本文对现有中药药效物质基础的几种研究方法进行了分类,并对其特点进行了介绍。The research of pharmacophore substance of traditional Chinese medicine(TCM) is the core of modernization of TCM. The material basis of clinical treatment of TCM is clarified scientifically that is the ultimate goal of research on the pharmacodynamics of TCM. At present, the main research methods of material basis of TCM include chemical separation and analysis, biochromatography, virtual screening and so on. In this paper, several existing research methods are classified and their characteristics are introduced.

关 键 词：中药 药效成分 研究方法 

分 类 号：R285[医药卫生—中药学]