人血白蛋白在综合医院的应用状况及药学干预效果调查分析  

Investigation and analysis of the application status of human serum albumin in general hospitals and the effect of pharmaceutical intervention

作　　者：石春勤[1] 陈荧[1] 张小妹 李秀华[1] SHI Chun-qin;CHEN Ying;ZHANG Xiao-mei(Department of Pharmacy,Foshan Gaoming District People’s Hospital,Foshan 528500,China)

机构地区：[1]佛山市高明区人民医院药学部,528500

出　　处：《中国现代药物应用》2019年第7期159-162,共4页Chinese Journal of Modern Drug Application

摘　　要：目的调查分析人血白蛋白在综合医院的应用状况及药学干预效果。方法选取120份2016年1～12月本院20%人血白蛋白注射液的使用数据作为干预前,不进行药学干预;另选取120份2017年1～12月本院20%人血白蛋白注射液的使用数据作为干预后,进行药学干预;对比药学干预前后人血白蛋白的使用情况。结果干预前,人血白蛋白消耗数量为(1190±2)瓶,消耗金额为(48.55±2.10)万元;干预后,人血白蛋白消耗数量为(581±3)瓶,消耗金额为(23.70±2.11)万元,干预前后比较差异具有统计学意义(P<0.05)。干预前后本院人血白蛋白的用药科室分布主要集中在骨一科、普外科、重症监护病房(ICU)、肿瘤科和产科,其中普外科、肿瘤科、产科、骨二科下降幅度较大。干预后治疗低蛋白血症例数明显少于干预前,差异具有统计学意义(P<0.05)。干预后新生儿高胆红素血症例数明显多于干预前,差异具有统计学意义(P<0.05)。使用人血白蛋白注射液患者的血清白蛋白(Alb)分布区间主要集中在30 g/L>Alb≥25 g/L。干预前后Alb≤25 g/L、35 g/L>Alb≥30 g/L、40 g/L>Alb≥35 g/L、≥40 g/L例数比较,差异具有统计学意义(P<0.05)。干预后人血白蛋白注射液不合理使用率为6.67%,明显低于干预前的19.17%,差异具有统计学意义(P<0.05)。结论人血白蛋白在本院使用量高且存在不合理使用的情况,药学干预减少了临床消耗,减轻患者负担并有效规范了应用的合理性。Objective To investigate and analyze the application status of human serum albumin in general hospitals and the effect of pharmaceutical intervention.Methods 120 data of 20%human serum albumin injection used during January^December 2016 were selected as data before intervention,with no pharmaceutical intervention,and 120 data of 20%human serum albumin injection used in our hospital during January^December 2017 were selected as data after intervention,with pharmaceutical intervention.The human albumin use before and after pharmaceutical intervention was compared.Results Before intervention,the amount of human albumin consumption was(1190±2)bottles and the amount of consumption was(4855±210)ten thousand yuan.After the intervention,the amount of human albumin consumption was(581±3)bottles and the amount of consumption was(2370±21.11)ten thousand yuan.Their difference was statistically significant(P<0.05).Before and after the intervention,the distribution of human albumin in the hospital was mainly concentrated in the Department one of Bone,Department of General Surgery,Intensive Care Unit(ICU),Oncology and Obstetrics.Among them,Department of General Surgery,Oncology,Obstetrics and Osteology decreased greatly.After intervention,the number of hypoproteinemia cases was significantly less than that before intervention,and the difference was statistically significant(P<0.05).After intervention,the number of neonatal hyperbilirubinemia cases was significantly more than that before intervention,the difference was statistically significant(P<0.05).Distribution of serum albumin(Alb)in patients using human serum albumin injection was mainly concentrated in 30 g/L>Alb>25 g/L.There were statistically significant differences in the number of cases with Alb<25 g/L,35 g/L,Alb<30 g/L,40 g/L,Alb<35 g/L and<40 g/L before and after intervention(P<0.05).After intervention,patients irrational use rate of human serum albumin injection after 6.67%,which was intervention was significantly lower 19.17%that before intervention,and the di

关 键 词：人血白蛋白 药学干预 合理用药 

分 类 号：R95[医药卫生—药学]