声辐射力脉冲成像技术评价低温后复温兔肝脏改变的初步研究  

Preliminary Study of Acoustic Radiation Force Impulse Technique Estimating the Change of Liver in Rabbits Under Low Temperature Then Resume Temperature

作　　者：毕名森 曹军英 张筠 高越 里子彧 张岩 孙钰 Bi Mingsen;Cao Junying;Zhang Yun;Gao Yue;Li Ziyu;Zhang Yan;Sun Yu(Department of Ultrasound,General Hospital of Northern Theater Command,Shenyang,Liaoning 110016,China)

机构地区：[1]北部战区总医院超声科,沈阳市110016

出　　处：《中国超声医学杂志》2019年第4期372-375,共4页Chinese Journal of Ultrasound in Medicine

基　　金：2013年度全军后勤科研调整完善计划面上新上项目(No.CSY13J005)

摘　　要：目的评估声辐射力脉冲成像(ARFI)技术在低温后复温条件下兔肝脏改变中的应用价值。方法首先将新西兰大白兔放置于-25℃的环境中低温8h,然后立即将其放置在23℃的环境中进行复温,分别在常温下以及低温8h (T_0)、低温后复温(T_1～T_8)9个时间点对实验兔肝脏的右叶进行常规超声及ARFI技术检查。结果实验兔肝脏右叶的回声和前后径没有发生明显改变。实验兔肝脏右叶的SWV值在T_0～T_1时间段急剧上升,T_1～T_4时间段先降低后升高,T_4～T_8时间段再逐渐降低。T_0～T_7各时间点的SWV值均大于常温,差异具有统计学意义(P<0.05),T_1～T_8各时间点的SWV值均小于T_0,差异具有统计学意义(P<0.05)。结论 ARFI技术可以评估低温后复温兔肝脏的改变,对临床判断低温后复温肝脏的改变情况有一定的应用价值。Objective To evaluate the value of acoustic radiation force impulse(ARFI)technique in the evaluation of the change of liver in rabbits under Low Temperature Then Resume Temperature conditions.Methods Sixteen New Zealand rabbits were placed in -25℃environment for 8 hours,then in 23℃ environment resumed temperature.Ultrasonic examinations were performed at room temperature,the time of T0 and the time of T1-T4.The right lobe of liver were evaluated by two-dimensional ultrasound and ARFI technique.Results No significant changes were found in the echo and the thickness of right lobe.Shear wave velocity(SWV)of right lobe raised heavily from T0 to T1 and first descended and then raised from T1 to T4 gradually,then it descended from T4 to T8 gradually.Significant difference of SWV of right lobe of liver were found from T0 to T7 compared with that at room temperature(P<0.05).Significant difference of SWV of right lobe of liver were found from T1 to T8 compared with that at T0(P<0.05).ConclusionsARFI Technique can estimate the change of liver in rabbits under Low Temperature Then Resume.It has the value of application in estimating the change of damaged liver under low temperature then resume for clinical diagnosis.

关 键 词：声脉冲辐射力 低温后复温 剪切波 肝脏 

分 类 号：R445.1[医药卫生—影像医学与核医学] R575[医药卫生—诊断学]