闭环靶控吸入七氟烷在新生儿腹部外科手术中的应用效果  

Application effect of closed-loop target-controlled inhalation of sevoflurane in neonatal abdominal surgery

作　　者：杜文康 林丽佳 张明[1] 成黎明[1] 李超[1] DU Wen-kang;LIN Li-jia;ZHANG Ming;CHENG Li-ming;LI Chao(Anesthesiology Department, Kunming Children's Hospital, Kunming 650228;Medical Department, the Third People's Hospital of Kunming City, Kunming 650041, China)

机构地区：[1]昆明市儿童医院麻醉科,云南昆明650228 [2]昆明市第三人民医院医务科,云南昆明650041

出　　处：《临床医学研究与实践》2019年第11期7-8,共2页Clinical Research and Practice

基　　金：云南省卫生科技计划项目(No.2016NS128)

摘　　要：目的探究闭环靶控吸入七氟烷在新生儿腹部外科手术中的应用效果。方法将本院收治的择期行剖腹探查手术的50例肠闭锁新生儿随机分为闭环靶控吸入组(T组)和新鲜气体控制吸入组(F组),每组25例。两组患儿均采用七氟烷诱导气管插管。麻醉维持时,T组靶控呼出七氟烷浓度为3.0%,F组持续吸入3.0%七氟烷。比较两组的麻醉效果。结果两组患儿均顺利完成手术。两组T2、T3、T4时MAP、HR均低于T1、T5时(P<0.05)。T组T2、T3、T4时MAP、HR无显著差异(P>0.05),F组T2、T3、T4时MAP、HR差异显著(P<0.05)。T组七氟烷消耗量、自主呼吸恢复时间、拔管时间均优于F组,差异显著(P<0.05)。结论闭环靶控吸入七氟烷在新生儿腹部外科手术中应用效果显著,可使患儿血流动力学更稳定,促使术毕自主呼吸快速恢复,是一种理想的麻醉方法。Objective To explore the application effect of closed-loop target-controlled inhalation of sevoflurane in neonatal abdominal surgery. Methods Fifty neonates with intestinal atresia who underwent exploratory laparotomy surgery were randomly divided into closed-loop target-controlled inhalation group(T group) and fresh gas-controlled inhalation group(F group), with 25 cases in each group. Sevoflurane was used to induce tracheal intubation in both groups. When anesthesia was maintained, target-controlled expiratory sevoflurane concentration was 3.0% in the group T, while the continuous inhalation of sevoflurane concentration was 3.0% in the group F. The anesthetic effects of the two groups were compared. Results The operations were successfully completed in both groups. The MAP and HR at T2, T3 and T4 in both groups were lower than those at T1 and T5(P<0.05). There were no significant differences in MAP and HR at T2, T3 and T4 in the group T(P>0.05), but there were significant differences in MAP and HR at T2, T3 and T4 in the group F(P <0.05). Sevoflurane consumption, spontaneous breathing recovery time and extubation time in the group T were better than those in the group F(P <0.05). Conclusion Closed-loop target-controlled inhalation of sevoflurane in neonatal abdominal surgery has a significant effect, which can make the hemodynamics of children more stable, and promote the rapid recovery of spontaneous breathing after operation. It is an ideal anesthetic method.

关 键 词：新生儿 麻醉 闭环靶控吸入 七氟烷 

分 类 号：R726.1[医药卫生—儿科]