超声检查在评估老年痛风患者治疗依从性中的应用研究  

Application of Ultrasonography in Evaluating the Complaince of the Elderly with Gout

作　　者：李挺[1] 陈志威[1] 李志勇 陈洁 王晓栋[1] 陈盛[1] 杜蕙[1] Li Ting;Chen Zhiwei;Li Zhiyong;Chen Jie;Wang Xiaodong;Chen Sheng;Du Hui(Department of Rheumatology,Renji Hospital Affiliated to Shanghai Jiao Tong University,Shanghai,201112;Department of Internal Medicine,Pujiang Community Health Service Center,Minhang District,Shanghai,201112,P.R.China)

机构地区：[1]上海交通大学医学院附属仁济医院南院风湿科,上海201112 [2]上海市闵行区浦江镇社区卫生服务中心,上海201112

出　　处：《老年医学与保健》2019年第2期201-205,共5页Geriatrics & Health Care

基　　金：上海申康医院发展中心郊区三级医院临床能力建设项目(SHDC12014904)

摘　　要：目的评估骨骼肌肉超声检查对老年痛风患者降尿酸治疗依从性的影响。方法 2015年6月—2017年12月,在上海交通大学医学院附属仁济医院南院风湿科疑似痛风的老年患者121例,年龄60～82岁,平均年龄(67.9±6.6)岁。受试者分为观察组和对照组2组,对照组仅接受降尿酸治疗;观察组在对照组的基础上于治疗后3个月时超声随访。2组在治疗后3个月、6个月时检测血尿酸水平,并评价受试者的治疗依从性。结果治疗后3个月,观察组全依从32例(59.3%),部分依从9例(16.7%),不依从13例(24.1%);对照组全依从21例(40.4%),部分依从14例(26.9%),不依从17例(32.7%),2组间依从性差异无统计学意义(P=0.145)。治疗后6个月,观察组全依从26例(48.1%),部分依从11例(16.7%),不依从17例(31.5%);对照组全依从12例(23.1%),部分依从10例(19.2%),不依从30例(57.7%),2组患者的治疗依从性差异有统计学意义(P=0.012),且2组血尿酸水平差异有统计学意义[(461.41±133.74)μmol/L vs (534.81±140.87)μmol/L,P=0.01]。结论超声辅助评估老年痛风患者治疗疗效可以改善患者的治疗依从性。Objective To explore the effect of ultrasonography on the compliance of the elderly with gout in urate-lowering therapy.Methods 121 elderly with suspected gout,aged from 60 to 82 years with the average of(67.9±6.6),were selected during the period from June,2015 to Dec.,2017 and were divided into 2 groups:observation group and control group;urate-lowering therapy was given to the elderly in both groups and the ultrasound follow-up was made to the elderly in observation group 3 months after treatment;the detection of serum uric acid level was performed on the elderly in the 2 groups at the time point of 3 months and 6 months after treatment,and the compliance of the elderly was evaluated.Results 3 months after treatment,total compliance was found in 32 cases(59.3%),partial compliance in 9 cases(16.7%)and non-compliance in 13 cases(24.1%)in observation group while those were in 21 cases(40.4%),in 14 cases(26.9%)and in 17 cases(32.7%)in control group,the difference in compliance between the 2 groups was of no statistical significance(P=0.145);6 months after treatment,the total compliance was found in 26 cases(48.1%)in observation group and in12 cases(23.1%)in control group,partial compliance in 11 cases(16.7%)and in 10 cases(19.2%)and non-compliance in 17 cases(31.5%)and 30 cases(57.7%),the difference in compliance between the 2 groups was of statistical significance(P=0.012);the difference in the levels of serum uric acid between the 2 groups was of statistical significance[(461.41±133.74)μmol/L vs(534.81±140.87)μmol/L,P=0.01].Conclusions The application of ultrasonography in curative effect evaluation can improve the compliance of the elderly with gout.

关 键 词：痛风 超声检查 尿酸 药物治疗依从性 

分 类 号：R445.1[医药卫生—影像医学与核医学] R589.7[医药卫生—诊断学]